β-Cyclodextrin incorporated carbon nanotube-modified electrode as an electrochemical sensor for rutin

He, Jing-Lin; Yang, Yibin; Yang, Xin; Liu, Yanli; Liu, Zhihang; Shen, Guo‐Li; Yu, Ru‐Qin

doi:10.1016/j.snb.2005.04.009

Cited by 125 publications

(52 citation statements)

References 29 publications

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“…When compared to other electrodes described in literature, the LOD is much lower to the CNT sensor that falls in the 10 -7 -10 -8 mol L -1 range. 15,19,21,30,31 The LOD is comparable with that found with the graphite-poliuretane composite electrode 16 in the order of 10 -9 mol L -1 .…”

Section: Discussionsupporting

confidence: 55%

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The use of a graphite-silicone rubber composite electrode in the determination of rutin in pharmaceutical formulation

Santos

Mazo

Cavalheiro

2008

J. Braz. Chem. Soc.

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O uso de um eletrodo compósito à base de grafite de borracha de silicone (GSR) na determinação de rutina, (vitamina P), por voltametria de pulso diferencial, é descrito. Voltamogramas cíclicos da rutina apresentaram um par de picos de oxidação/redução no GSR em 0,411 e 0,390 V (vs. ECS), respectivamente, em solução tampão Britton-Robinson (B-R) pH 4,0. Em voltametria de pulso diferencial (DPV), após a otimização das condições, o pico de oxidação em 0,370 V (vs. ECS) foi usado na determinação quantitativa de rutina. Neste caso, um intervalo linear entre 5,0-50,0×10 -8 mol L -1 foi observado com um limite de detecção de 1,8×10 -8 mol L -1 . Recuperações de 94 a 113% foram observadas. A superfície do eletrodo foi renovada por polimento, com uma repetibilidade de 1,09 ± 0,06 µA (n = 10) para a corrente de pico. A rutina foi determinada em uma formulação farmacêutica e os resultados concordaram com aqueles obtidos de um método oficial com 95% de confiança.The possibility of using a graphite silicone-rubber composite electrode (GSR) in a differential pulse voltammetric(DPV) procedure for rutin (vitamin P) determination is described. Cyclic voltammograms of rutin presented a reversible pair of oxidation/reduction peaks respectively at 0.411 and 0.390 V (vs. SCE) at the GSR surface in Britton-Robinson(B-R) buffer solution pH 4.0. In DPV after optimization of conditions, an oxidation peak at 0.370 V (vs. SCE) was used to quantitative determination of rutin in B-R buffer solution pH 4.0. In this case a linear dynamic range of 5.0×10 -8 to 50.0×10 -8 mol L -1 was observed with a detection limit of 1.8×10 -8 mol L -1 for the analyte. Recoveries from 94 to 113% were observed. The electrode surface was renewed by polishing after each determination, with a repeatability of 1.09 ± 0.06 µA (n = 10) peak current. Rutin was determined in a pharmaceutical formulation using the proposed electrode and the results agreed with those from an official method within 95% confidence level.

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Section: Discussionsupporting

confidence: 55%

“…He et al 21 modified a GC electrode with multi-wall carbon nanotubes (MWCNT)-β-cyclodextrin film. The electrochemical behavior of rutin at a chemically modified electrode was investigated by CV.…”

Section: Introductionmentioning

confidence: 99%

The use of a graphite-silicone rubber composite electrode in the determination of rutin in pharmaceutical formulation

Santos

Mazo

Cavalheiro

2008

J. Braz. Chem. Soc.

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“…CNTs are simply dispersed in a β-CD solution with sonication, resulting in a 2 mg/mL suspension (He et al, 2006). An aliquot of this suspension is dropped on a glassy carbon electrode (GCE) followed by air drying to form a CNT modified electrode.…”

Section: Dispersion Of Cnts In Solventsmentioning

confidence: 99%

Advances in carbon nanotube based electrochemical sensors for bioanalytical applications

Vashist

Zheng

Al‐Rubeaan

et al. 2011

Biotechnology Advances

407

218

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Electrochemical (EC) sensing approaches have exploited the use of carbon nanotubes (CNTs) as electrode materials owing to their unique structures and properties to provide strong electrocatalytic activity with minimal surface fouling. Nanofabrication and device integration technologies have emerged along with significant advances in the synthesis, purification, conjugation and biofunctionalization of CNTs. Such combined efforts have contributed towards the rapid development of CNT-based sensors for a plethora of important analytes with improved detection sensitivity and selectivity. The use of CNTs opens an opportunity for the direct electron transfer between the enzyme and the active electrode area. Of particular interest are also excellent electrocatalytic activities of CNTs on the redox reaction of hydrogen peroxide and nicotinamide adenine dinucleotide, two major by-products of enzymatic reactions. This excellent electrocatalysis holds a promising future for the simple design and implementation of on-site biosensors for oxidases and dehydrogenases with enhanced selectivity. To date, the use of an anti-interference layer or an artificial electron mediator is critically needed to circumvent unwanted endogenous electroactive species. Such interfering species are effectively suppressed by using CNT based electrodes since the oxidation of NADH, thiols, hydrogen peroxide, etc. by CNTs can be performed at low potentials. Nevertheless, the major future challenges for the development of CNT-EC sensors include miniaturization, optimization and simplification of the procedure for fabricating CNT based electrodes with minimal non-specific binding, high sensitivity and rapid response followed by their extensive validation using "real world" samples. A high resistance to electrode fouling and selectivity are the two key pending issues for the application of CNT-based biosensors in clinical chemistry, food quality and control, waste water treatment and bioprocessing.

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“…An electrochemical sensor modified with multi-walled carbon nanotubes/ -cyclodextrin (MWNTs/ -CD) film was fabricated for the determination of rutin [85]. The electrochemical behavior of rutin at the chemically modified electrode was investigated by cyclic voltammetry (CV).…”

Section: Applications Of Cyclodextrin Modified Electrode In Pharmaceumentioning

confidence: 99%

Electrochemistry of Cyclodextrin Inclusion Complexes of Pharmaceutical Compounds

Radi¹

2010

TOCBMJ

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Electrochemistry of cyclodextrins (CDs) and cyclodextrin inclusion complexes with different pharmaceutical compounds is reviewed. The article highlights some electrochemical investigations of the CD-drugs interactions in solution. Cyclodextrin modified electrodes and their applications as electrochemical sensors in pharmaceutical analysis based on the self-assembly of CD derivatives on metal electrodes and nanoparticles, and cyclodextrin-modified multiwalled carbon nanotubes are also discussed.

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β-Cyclodextrin incorporated carbon nanotube-modified electrode as an electrochemical sensor for rutin

Cited by 125 publications

References 29 publications

The use of a graphite-silicone rubber composite electrode in the determination of rutin in pharmaceutical formulation

The use of a graphite-silicone rubber composite electrode in the determination of rutin in pharmaceutical formulation

Advances in carbon nanotube based electrochemical sensors for bioanalytical applications

Electrochemistry of Cyclodextrin Inclusion Complexes of Pharmaceutical Compounds

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