2017
DOI: 10.1016/j.ijbiomac.2017.05.191
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β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and ROS production in human hepatocytes

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Cited by 19 publications
(8 citation statements)
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“…The treatment of protease K, DNase I, and RNase can conveniently and efficiently remove proteins and nucleic acids [ 21 ]. Crude polysaccharides often contain dark impurities that require decolorization, typically with 10% H 2 O 2 [ 22 ], through the use of oxidants to destroy the chromogenic groups of pigments. Other impurities, such as monosaccharides, oligosaccharides, inorganic salts, and low-molecular-weight nonpolar substances, can be removed using dialysis.…”
Section: Isolation and Purification Of Bioactive Compounds From ...mentioning
confidence: 99%
“…The treatment of protease K, DNase I, and RNase can conveniently and efficiently remove proteins and nucleic acids [ 21 ]. Crude polysaccharides often contain dark impurities that require decolorization, typically with 10% H 2 O 2 [ 22 ], through the use of oxidants to destroy the chromogenic groups of pigments. Other impurities, such as monosaccharides, oligosaccharides, inorganic salts, and low-molecular-weight nonpolar substances, can be removed using dialysis.…”
Section: Isolation and Purification Of Bioactive Compounds From ...mentioning
confidence: 99%
“…The polysaccharides of A. cinnamomea also have therapeutic potential as an adjuvant in the immunomodulation treatment of allergic asthma (Liu et al, 2010). In addition, the water-soluble polysaccharides comprising β-glucan in A. cinnamomea can alleviate the inflammatory response induced by lipopolysaccharide (Chen et al, 2017).In the present study, the therapeutic and regulatory or restoration effects of intracellular polysaccharide from A. cinnamomea on antibiotic-induced diarrhea and disorder in mouse intestinal flora were investigated. A new concept and theoretical basis for developing novel multifunctional prebiotics were provided.…”
Section: Introductionmentioning
confidence: 95%
“…Numerous studies in β-1,3-glucan have confirmed its property of anti-inflammatory, immune-enhancing, and anti-oxidation in aquatic animals such as white shrimp ( 7 9 ), marine swimming crab ( Portunus trituberculatus ), hybrid striped bass ( Morone chrysops × M. saxatilis ) ( 10 ), and large yellow croaker ( Pseudosciaena crocea ) ( 11 ). Evidence from human hepatocytes suggested that β-1,3-glucan could attenuate inflammation and accumulation of reactive oxygen species (ROS) induced by lipopolysaccharide ( 12 ). Similarly, the results in rainbow trout ( Oncorhynchus mykiss ) ( 13 ), silver catfish ( Rhamdia quelen ) ( 14 ), and common carp ( Cyprinus carpio L) ( 15 ) suggested that β-glucan (including β-1,3-glucan) could reduce the intestinal inflammatory response and oxidative stress induced by the challenge of Aeromonas hydrophila or tissue damage.…”
Section: Introductionmentioning
confidence: 99%