2021
DOI: 10.1016/j.ijbiomac.2021.05.065
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β-Glucan: A dual regulator of apoptosis and cell proliferation

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Cited by 44 publications
(20 citation statements)
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“…Laminarin is a dual regulator of apoptosis and cell proliferation, similar to β-Glucan [96]. Marine-derived antioxidant polysaccharides have three distinct mechanisms, including scavenging the ROS, regulating the antioxidant system or oxidative stress-mediated signaling pathways [97] (Figure 3a).…”
Section: Antioxidant Activitymentioning
confidence: 99%
“…Laminarin is a dual regulator of apoptosis and cell proliferation, similar to β-Glucan [96]. Marine-derived antioxidant polysaccharides have three distinct mechanisms, including scavenging the ROS, regulating the antioxidant system or oxidative stress-mediated signaling pathways [97] (Figure 3a).…”
Section: Antioxidant Activitymentioning
confidence: 99%
“…Yeast β-glucans enhance bowel motility and intestinal obstipation [58][59][60]. The main action mechanism after ingestion involves contact with pattern recognition receptors (PPRs) in the intestinal cells, which internalize fragments that will interact and activate the immune system [61]. Yeast BG also interferes with liver lipid metabolism, expressively changing the transcriptional profiles, and leading to a reduced lipid accumulation in obese mice livers [37].…”
Section: Discussionmentioning
confidence: 99%
“…In the intestinal lumen, pattern recognition receptors (PRRs) recognize β - d -glucans coming with food [ 73 ]. The primary PRR for the water-insoluble fraction of β - d -glucans is Dectin-1 expressed on the surface of macrophages and dendritic cells (DC), while the water-soluble portion of β - d -glucans can bind to Complement Receptor 3 (CR3) [ 13 ].…”
Section: Possible Molecular Mechanisms Of Oat β - ...mentioning
confidence: 99%