Биологически Активные Вещества Плодов Калины Обыкновенной

Перова, И Б; Жогова, А. А.; Cherkashin, Artemiy; Эллер, К И; Раменская, Г. В.; Самылина, И. А.

doi:10.30906/0023-1134-2014-48-5-32-39

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…Учитывая, что представители рода Caragana являются накопителями фенольных соединений [5], в частности, флавоноидов, ранее нами был проведён анализ полифенольных соединений водного извлечения надземной части C. jubata методом высокоэффективной жидкостной хроматографии (ВЭЖХ) [4,6]. В качестве основных флавоноидов в водном извлечении караганы были идентифицированы кверцитрин (6,03 мг/г), гиперозид (3,73 мг/г), мирицетин-3-рамнозид (2,04 мг/г), авикулярин (2,39 мг/г), ларицитрин-3-рамнозид (1,79 мг/г), 3-рамнозиды изорамнетина и сирингетина (1,77 мг/г) [4].…”

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Hepatoprotective activity of aqueous extract from Caragana jubata (Pall.) Poir. shoots in the model of acute hepatitis induced by acetaminophen in rats

et al. 2018

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The aim of the study was to investigate the hepatoprotective activity of an aqueous extract of Caragana jubata (Pall.) Poir. Acute experimental hepatitis was induced by acetaminophen administration of 1000 mg/kg. Studies were conducted in white Wistar rats. The aqueous extract of C. jubata demonstrated the hepatoprotective effect, comparable to that of the reference preparation "Carcil". This was manifested by the normalization of biochemical blood parameters (ALT, AST, alkaline phosphatase, cholesterol, total bilirubin) and antioxidant activity of liver homogenates, determined by the method based on oxidation of luminol induced by 2,2¢-azo-bis-2-amidinopropane. Normalization of morphofunctional indices was also shown in a histological study of liver of rats that received aqueous extract from C. jubata.

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Section: Introductionunclassified

Hepatoprotective activity of aqueous extract from Caragana jubata (Pall.) Poir. shoots in the model of acute hepatitis induced by acetaminophen in rats

et al. 2018

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Influence of Various Technological Factors on the Composition of Anthocyanins in Black Currant Wine Production

Макаров¹,

Макаров

Панасюк³

et al. 2019

Food Processing: Techniques and Technology

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Anthocyanins obtained from raw fruit have valuable biological and antioxidant properties, hence the relevance of any research aimed at the development of technological solutions for their maximum preservation in wine. The present research features the changes in qualitative and quantitative composition of anthocyanins found in black currant during wine production with the use of enzymatic maceration of the pulp. The authors determined the most effective ways of increasing the concentration of anthocyanins in the finished product. They used the method of pH-differential spectrophotometry to evaluate the total content of monomeric anthocyanins in the samples and the HPLC method to determine the concentration of individual anthocyanins. The DPPH and ABTS methods were used to measure the antioxidant activity. The pulp of black currant was treated according to four schemes: 1) heat maceration; 2) heat maceration with enzymatic treatment; 3) enzymatic maceration at the optimum temperature for enzyme activity; 4) enzymatic maceration at a low temperature. Eleven anthocyanins were identified in the black currant juice, most of which were glycosides of delphinidin and cyanidin. The highest extraction of anthocyanins was observed when the pulp was processed with the help of Fructozim Kolor enzyme preparation at 22–23°C during four hours. As a result, the proportion of delphinidins decreased while the proportion of cianidins rose by 9%. When the pulp was heated to ≥ 45°C, it led to an intensification of the redox process and formation of insoluble complexes of anthocyanins with the nitrogenous compounds, which reduced the total concentration of anthocyanins. It was established that in the process of fermentation, the anthocyanin concentration decreased by 19–58%, depending on the race of yeast. For fermentation of blackcurrant wort, the authors recommend the following races of yeast: Moscow 30, Blackcurrant 7, and UWY SP1. The research revealed that the antioxidant properties of black currant wort and wine increased when the total concentration of anthocyanins was high.

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In Vitro Evaluation of Antithrombotic and Anticoagulant Activity of Herbal Sources

ABDULLINA,

KUDASHKINA,

KHASANOVA

et al. 2024

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Objective: In vitro evaluate the antiaggregation and anticoagulation properties of aqueous plant extracts, including Viburnum opulus flowers and fruits, Urtica dioica leaves, Coffea arabica leaves, and shepherd's purse (Capsella bursa-pastoris) herb. Methods: In vitro assessment of anticoagulation activity was conducted by examining the impact on activated partial thromboplastin time (APTT), prothrombin time (PT), and fibrinogen levels. Anti-aggregation activity was evaluated using the Born turbidimetric method. Results: The research found that the phytoextracts examined did not impact the concentration of fibrinogen and PT. However, they did slightly prolong the APTT, and this effect was statistically significant compared to the control. Coffea arabica leaves, and Viburnum opulus fruit extracts showed substantial anticoagulant activity (30% and 29% sodium heparin, respectively; p-value <0.05 for both). Extracts of Viburnum opulus fruits and Coffea arabica leaves significantly prolong the latent period before collagen-induced platelet aggregation by up to 116.7% and 118.8% of the intact platelet index, respectively. Every sample analyzed showed a significant decrease in the maximum platelet aggregation amplitude compared to the control. The most notable impact was with Urtica dioica and Coffea arabica leaf extracts, which reduced the percentage to 85.9% and 89.2% of the control, respectively. These extracts exhibited 77.6% and 59.7% of the effectiveness of acetylsalicylic acid, with Coffea arabica extract showing a significant difference (p<0.05) compared to the reference drug. All plant extracts, except Capsella bursa-pastoris extract, which reduced this indicator, significantly prolonged the time needed to reach maximum aggregation. Coffea arabica extract had the most significant impact, showing 223.8% of the efficacy of acetylsalicylic acid (p<0.05). The extracts (excluding Capsella bursa-pastoris) significantly decreased the platelet aggregation rate. The most notable impact was observed with extracts of Viburnum opulus flowers and Coffea arabica leaves, which yielded an inhibitory effect on the rate of aggregation of acetylsalicylic acid (-10%/min relative to intact platelets, p<0.05), reducing aggregation rate by -5.2% and -6%/min compared to control, respectively. Conclusion: The samples analyzed in our study show weak anticoagulation activity, with the most noticeable effects in extracts of coffee leaves and viburnum fruits. Additionally, we found that the antiaggregation activity of the extracts of coffee leaves, nettles, and viburnum fruits was much more substantial, comparable to or even surpassing the effect of acetylsalicylic acid in some cases. Keywords: Anticoagulation properties, antiaggregation activity, Viburnum opulus, Urtica dioica, Coffea arabica, Capsella bursa-pastoris.

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Биологически Активные Вещества Плодов Калины Обыкновенной

Cited by 3 publications

References 6 publications

Hepatoprotective activity of aqueous extract from Caragana jubata (Pall.) Poir. shoots in the model of acute hepatitis induced by acetaminophen in rats

Hepatoprotective activity of aqueous extract from Caragana jubata (Pall.) Poir. shoots in the model of acute hepatitis induced by acetaminophen in rats

Influence of Various Technological Factors on the Composition of Anthocyanins in Black Currant Wine Production

In Vitro Evaluation of Antithrombotic and Anticoagulant Activity of Herbal Sources

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