This article presents research results of national research universities (NRU) and federal universities (FU) contribution to the Project of competitiveness enhancement of the leading Russian universities among global research and education centers (Project 5-100). The following indicators were analyzed: publications, indexed in Web of Science and Scopus databases, share of international students and faculty, share of young employees and staff with PhD, performance in international rankings, etc. The analysis was based on 41 quantitative and 11 qualitative indicators. In the analysis the following data sources were used: statistical forms 1-Monitoring, rankings agencies data, etc. It has been determined that the most influence on the Russian education competitiveness enhancement in the world belongs to the leading NRU – participants of Project 5-100. The article analyzes the contribution of federal universities in the implementation of the Project 5-100.