Синтез И Некоторые Превращения 3-Амино-Спиро(бензо[h]хиназолин-5,1'-Циклогептанов)

Маркосян, Ашот Ишханович; Айвазян, Ани Сережаевна

doi:10.31857/s0514749221030095

ZhOrgKhim

2021

DOI: 10.31857/s0514749221030095

|View full text |Cite

Синтез И Некоторые Превращения 3-Амино-Спиро(бензо[h]хиназолин-5,1'-Циклогептанов)

Ашот Ишханович Маркосян¹,

Ани Сережаевна Айвазян²

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Synthesis, some transformations and antibacterial activity of 5H-spiro[benzo[h][1,2,4]triazolo[3,4-b]quinazoline6,1′-cycloheptane]-7(11H)-ones

Markosyan,

Ayvazyan,

Gabrielyan

et al. 2023

Žurnal obŝej himii

View full text Add to dashboard Cite

Condensation of 2-thioxo-2,3-dihydro-1 H -spiro[benzo[ h ]quinazoline-5,1′-cycloheptane]-4(6 H )-one with hydrazine hydrate afforded 2-hydrazinyl-3 H -spiro[benzo[ h ]quinazoline-5,1′-cycloheptane]-4(6 H )-one. The reaction of the latter with orthoformic acid ethyl ester or carbon disulfide yielded 5 H -spiro[benzo[ h ][1,2,4]triazolo[3,4- b ]quinazoline-6,1′-cycloheptane]-7(11 H )-one and 9-mercapto-5 H -spiro[benzo[ h ][1,2,4]triazolo[3,4- b ] quinazoline-6,1 ‘-cycloheptane]-7(11 H )-one, respectively. Alkylation of the latter with methyl and ethyl iodides, allyl bromide, and benzyl chloride gave 9-sulfanyl-substituted 5 H -spiro[benzo[ h ][1,2,4]triazolo[3,4- b ]quinazoline-6,1′-cycloheptane]-7(11 H )-ones. The synthesized compounds exhibited antibacterial properties.

show abstract

Synthesis, some transformations and antibacterial activity of 5H-spiro[benzo[h][1,2,4]triazolo[3,4-b]quinazoline6,1′-cycloheptane]-7(11H)-ones

Markosyan,

Ayvazyan,

Gabrielyan

et al. 2023

Žurnal obŝej himii

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Синтез И Некоторые Превращения 3-Амино-Спиро(бензо[h]хиназолин-5,1'-Циклогептанов)

Cited by 1 publication

References 0 publications

Synthesis, some transformations and antibacterial activity of 5<i>H</i>-spiro[benzo[<i>h</i>][1,2,4]triazolo[3,4-<i>b</i>]quinazoline6,1′-cycloheptane]-7(11<i>H</i>)-ones

Synthesis, some transformations and antibacterial activity of 5<i>H</i>-spiro[benzo[<i>h</i>][1,2,4]triazolo[3,4-<i>b</i>]quinazoline6,1′-cycloheptane]-7(11<i>H</i>)-ones

Contact Info

Product

Resources

About