ФИЗИОЛОГИЯ ЛЕГОЧНЫХ ВЕНОЗНЫХ СОСУДОВ, "Российский Физиологический Журнал Им. И.М. Сеченова"

Evlakhov, V. I.; Poiasov, I Z

doi:10.7868/s0869813918100027

Cited by 3 publications

(1 citation statement)

References 35 publications

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“…The high rate of gas exchange is facilitated by the architectonics of the intraorgan blood vessels of the lungs, which ensures an even distribution of blood within the small circle of blood circulation. The pulmonary vessels are capable of active tonic activity, despite the fact that the resistance to the blood flow in them is an order of magnitude lower than in the large circle [1,2]. About 10% of the blood circulating in the human body falls on the small circle vessels, which ensure a high compliance of the pulmonary circulation [3].…”

Section: Introductionmentioning

confidence: 99%

Paravasal Connective Tissue Parameters Vs. Morpho-Functional Indicators In The Intraorgan Blood Vessels Of The Younger Men Lungs

Nickel

Ефремова

2021

Russ Open Med J

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Objective — The objective of this research was to identify correlations between the paravasal components connective tissue of the blood vessels of lungs and their morpho-functional parameters. Material and Methods — In order to determine the structure of the paravasal connective tissue, the histotopographic and histological examination of lung preparations of 20 men corpses of the first mature age period was held, to determine the capacity and capacitive characteristics of the vascular bed, the determination of the Kernogan index (IK) and the veno-arterial index (VAI) were carried out. Results — It was ascertained that in the structure of the paravasal connective tissue two layers could be conditionally distinguished – the "central" and "peripheral", differing in the architectonics of the fibrous component, the nature of interaction with nearby anatomical structures. It was also revealed that infrared venous vessels IK was expressed in a greater degree in comparison with arterial. When determining VAI vascular, the channel revealed that the area of venous vessels prevailed over the arterial area. Besides, the clear correlation relationships of the structural elements of the paravasal connective tissues were investigated with arterial and venous vessel capacity values and their capacitive characteristics. Conclusion — The presence of correlation relationships confirmed a clear interaction between structural organization of the paravasal connective tissue and the functional activity of the blood vessels, providing optimal hemodynamic conditions in the organ.

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Section: Introductionmentioning

confidence: 99%

Paravasal Connective Tissue Parameters Vs. Morpho-Functional Indicators In The Intraorgan Blood Vessels Of The Younger Men Lungs

Nickel

Ефремова

2021

Russ Open Med J

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Pulmonary artery denervation in pulmonary hypertension: physiological and clinical aspects

2021

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Роль Паратиреоидного Гормона В Функциональной Активности Сердечно-Сосудистой Системы

Минасян¹

2022

MSEJ

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A comprehensive comparative study of the contractile ability of aorta and systemic hemodynamic responses has been performed in animals with impaired calcium-phosphorus metabolism, caused by removing the parathyroid glands and under the influence of parathyroid hormone (PTH). In addition, the analysis of its pharmacological mechanism of action has been performed. The results of aorta contractility in vitro studies in control and parathyreoidectomied rats as well as under the influence of PTH physiological concentrations (10-10 M), L-blocker of Са-channels of myocyte membrane - verapamil (10-5 M) and a phosphodiesterase inhibitor - theophylline (10-4 M) demonstrated the possible regulatory impact of PTH and related disorders to reduce the aorta contractility induced by adrenaline (10-5 M) and its relaxation caused by papaverine (10-4 M). Further, in vivo studies revealed that the increase of heart rate (HR) and the decrease of blood pressure (BP) in rats with impaired calcium-phosphorus metabolism is caused by the parathyroidectomy. Special attention should be paid to the fact that we have observed increased reactivity of aortic myocytes in parathyreoidectomied animals in response to the action of adrenaline and papaverine, as well as a sharp increase in adrenoreactivity of heart and blood vessels, thus the increase in HR and BP in response to the usual doses of adrenaline. The clinical significance of this phenomenon is undeniable. The possibility of a sharp increase of BP in patients with PTH-dependent disturbance of calcium-phosphorus metabolism and the potential of development of severe vascular complications (strokes, heart attacks) in the context of emotional and stress influences should be considered in clinically similar conditions.

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ФИЗИОЛОГИЯ ЛЕГОЧНЫХ ВЕНОЗНЫХ СОСУДОВ, "Российский Физиологический Журнал Им. И.М. Сеченова"

Cited by 3 publications

References 35 publications

Paravasal Connective Tissue Parameters Vs. Morpho-Functional Indicators In The Intraorgan Blood Vessels Of The Younger Men Lungs

Paravasal Connective Tissue Parameters Vs. Morpho-Functional Indicators In The Intraorgan Blood Vessels Of The Younger Men Lungs

Pulmonary artery denervation in pulmonary hypertension: physiological and clinical aspects

Роль Паратиреоидного Гормона В Функциональной Активности Сердечно-Сосудистой Системы

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