化学療法が奏効した鼻翼原発の硬化型横紋筋肉腫症例

Abstract

Sclerosing rhabdomyosarcoma is a rare soft tissue tumor, and the subtype accounts for only about 10％ of all rhabdomyosarcomas. We herein report a case of sclerosing rhabdomyosarcoma originating from the nasal wing, which responded well to chemotherapy. A 26-year-old man received therapy for sclerosing rhabdomyosarcoma of the left nasal wing. The tumor size was extremely reduced after three courses of neoadjuvant chemotherapy which made tumor excision easier during the subsequent surgery. After the surgery, four courses of chemotherapy were performed as adjuvant therapy. The patient has remained recurrence-free for thirteen months after the therapy. This case suggests that chemotherapy may be a practical choice for the treatment of sclerosing rhabdomyosarcoma in head and neck sites, whose prognosis is commonly considered poor.