Sclerosing rhabdomyosarcoma is a rare soft tissue tumor, and the subtype accounts for only about 10% of all rhabdomyosarcomas. We herein report a case of sclerosing rhabdomyosarcoma originating from the nasal wing, which responded well to chemotherapy. A 26-year-old man received therapy for sclerosing rhabdomyosarcoma of the left nasal wing. The tumor size was extremely reduced after three courses of neoadjuvant chemotherapy which made tumor excision easier during the subsequent surgery. After the surgery, four courses of chemotherapy were performed as adjuvant therapy. The patient has remained recurrence-free for thirteen months after the therapy. This case suggests that chemotherapy may be a practical choice for the treatment of sclerosing rhabdomyosarcoma in head and neck sites, whose prognosis is commonly considered poor.
We herein report 14 cases of preoperatively diagnosed anaplastic thyroid carcinoma treated at our hospital between September 2002 and September 2021 and confirmed by postoperative histopathological examination. Treatment was based on the extent of lesions; we performed total pharyngo-laryngo-cervical esophagectomy in 2 cases, total thyroidectomy in 8 cases, and lobectomy in 4 cases. As a result, 3 patients show no evidence of disease, 1 patient is alive with disease, and 10 patients have died of disease. Local control was achieved in 3 cases of disease death. The 1-year overall survival rate was 57.1% and the local control rate was 57.1%. It is suggested that surgical treatment of anaplastic thyroid carcinoma may provide local control and contribute to improved prognosis.
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