It would be interesting to determine if dopamine (a monoamine catecholamine compounds) in the environment affect bacterial social and motility behaviors. Understanding this interaction in P. aeruginosa species could provide new insights into the regulation of the virulence of this pathogen in both environmental and clinical settings. In this case report, we examined two clinical isolates of Pseudomonas aeruginosa for their ability to produce biofilm with a chemotaxis behavior for the dopamine to explain this social behavior.
Infection with the fluorescent pathogen Pseudomonas aeruginosa leads to gastrointestinal infections, dermatitis, bacteremia and a variety of systemic infections. Thus, within a very complex chemosensory system this bacterium has requires an adaptive strategy to escape to the immune system. It chemosensory system has attracted a significant interest because of the very complex molecular diversity of this one (> 20 chemotaxis (che) genes). With this diversified chemotaxis system, this bacteria moves from cell to cell by a twitching motility and respond in a behavioral manner. For this, it can be viewed as an important prelude to infections and serious clinical challenge.
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