In this paper, we describe the case of a 45-year-old male who presented with recurrent swelling of the submandibular region. The last episode of the swelling was triggered post tooth extraction. There were associated features like increased temperature and leukocytosis. The patient was started on IV antibiotics and analgesics and with incision and drainage the patient improved with no sequelae.
Aim: To study the efficacy of Fresh Frozen Plasma (FFP) transfusion practice in patients with coagulation abnormalities varies in clinical practice.
Study Design: A retrospective study.
Place and Duration of Study: This study was conducted in Department of Transfusion Medicine, SMCH, Chennai, between the period of 2019-2020.
Methodology: The medical records of each patient receiving FFP transfusions that occurred in patients with coagulation abnormalities were reviewed and the data were collected based on pre-and post transfusion PT (>12 sec), APTT (>70sec) and INR (>1.5) and then analysed statistically. Patients with normal coagulation parameters were excluded from study.
Results: A total of 1259 units of fresh frozen plasma were transfused to 315 patients between the year 2019-2020. Of the 1259 units transfused 1133 units where transfused to 283 patients with coagulation abnormalities. Apparently 32 patients were excluded from the study as they had normal coagulation profile. Among 251 patients, 37 patients PT were greater than 12 seconds before FFP transfusion out of which the PT was corrected for 14 patients (37.8%) after FFP transfusion. In 228 patients APTT was greater than 70 seconds before FFP transfusion, out of which APTT was corrected in 18 patients (8%) after transfusion. INR values for all 251 patients were greater than1.5 before FFP transfusion, out of which INR was corrected in 84 patients (29%) after transfusion.
Conclusion: We conclude that FFP transfusions in patients with coagulation abnormalities maycorrects the defect only in less percentage of patient population, as in our study it corrects only an average of 31% of patient population.
Aim: To determine the transfusion trigger for cardiac surgery patients and to determine the transfusion pattern in these patients.
Study Design: A retrospective cross sectional observational study.
Place and Duration of Study: This study was conducted in Department of Transfusion Medicine, SMCH, Chennai, between the periods of 2017-2020.
Methodology: This study was done by reviewing the blood bank records for patients undergoing cardiac surgery from 2017 to 2020. Patients with other comorbid conditions like cirrhosis, malignancy, those who underwent emergency surgeries and death during the surgery were excluded from the study. Patient data like age, diagnosis, number of components transfused, preoperative hemoglobin, and details of surgery done on the respective patients were reviewed from the blood bank records.
Results: A total of 100 patients were included in the study. Mean age of the patients was 53.3 ± 13.6 years. In our sample population 73% of patients underwent CABG procedure and they received packed red blood cell transfusions. Among the PRBC transfusions 93% of patients received liberal transfusions and 7% of patients received restrictive transfusions. Majority of patients in our study population about 58% belong to 45-64 years of age group.
Conclusion: We found that most of the transfusions done in cardiac surgery patients were done on liberal transfusion strategy. Thus, we conclude in our study most of the transfusions done on cardiac surgery patients followed liberal transfusion strategy, which would be less harmful to the patients.
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