Cite as: Can Urol Assoc J 2014;8(1-2):e8-11. http://dx.doi.org/10.5489/cuaj.1261 Published online January 14, 2014.
AbstractIntroduction: We evaluate the efficiency of α-adrenergic antagonists on stone clearance after extracorporeal shock wave lithotripsy (ESWL) in patients with lower ureteral stones. Methods: A total of 356 patients with solitary lower ureteral stones who underwent single ESWL sessions were divided into 2 groups. Group 1 received our standard medical therapy, and Group 2 was treated with 0.4 mg/day tamsulosin for a maximum of 2 weeks. All patients were re-evaluated with plain film radiography and ultrasound each week during the treatment period. A computed tomography scan was systematically performed 3 months after ESWL. Results: In total, 82 of the 170 patients in Group 1 (48.2%) and 144 of the 186 patients in Group 2 (77.4%) (p = 0.002) were stonefree. Among the patients with stones 10 to 15 mm in diameter, the stone-free rate was 38.4% in Group 1 and 77.1% in Group 2 (p = 0.003). Average stone expulsion time was 10.6 days and 8.4 days in Groups 1 and 2, respectively. Ureteral colic occurred in 40 patients (23.5%) in Group 1, but only in 10 patients (5.3%) in Group 2 (p = 0.043). The only side effect of tamsulosin was slight dizziness in 5 of the 186 patients in Group 2 (2.6%). Conclusion: Adjunctive therapy with α1-adrenergic antagonists after ESWL is more efficient than, and equally as safe as, lithotripsy alone to manage patients with lower ureteral stones. The adding of α-blockers is more reliable and helpful for stones with a large dimension, and can also decrease stone elimination time and episodes of ureteral colic.
images in clinical medicineT h e n e w e ng l a n d j o u r na l o f m e dic i n e n engl j med 366;17 nejm.org april 26, 2012
1625A 22-year-old man with a history of uncorrected left cryptorchidism presented after 7 days of left groin pain. A genitourinary examination was performed, which revealed that his left inguinal region was swollen because of a palpable, tender mass that was 5 cm in greatest dimension. No testicle was palpable in the ipsilateral hemiscrotum (Panel A). An ultrasound examination of the inguinal area revealed a heterogeneous testicle, with no blood flow on Doppler examination. Surgical exploration confirmed torsion of the undescended testis (Panel B). Torsion of a cryptorchid testicle is an uncommon condition but is reported to occur more frequently than torsion of a normally descended testis. In a patient presenting with pain and uncorrected cryptorchidism, a testicular tumor must also be considered in the differential diagnosis. In this patient, final pathological examination revealed a diffusely ischemic, necrotic testicle with no malignant tumor.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.