Comprehensive survey allowed to define the cause of OH. Minimally invasive organ-sparing surgery has satisfactory immediate and remote results in these patients.

Total pancreatectomy is advisable for pancreatic adenocarcinoma if its volume is over 31.8% of total pancreas according to 3D CT-scans. 3D-modeling improves preoperative assessment of resectability, accuracy of determining of tumor localization and identifying vascular invasion.

No abstract

Background: Laparoscopic distal pancreatic resection has gained acceptance and being practised in major HPB units. Laparoscopic pancreatico-duodenal resections are technically demanding and benefit of this approach has been a matter of debate over the past decade. We aim to analyse our early experience in laparoscopic pancreatico -duodenal resections. Methods: From November 2012 to August 2015, we have performed 8 pancreatico-duodenal resections. There were 2 total pancreatectomies and 6 Whipple's resections. The laparoscopic approach was using 5 ports with patient in supine position. We describe the patient characteristics, techniques and short-term outcomes. Results: The median age was 56 years (39e75) and M:F was 2:1. The Median BMI was 21 (17.5e23.5). The major indication was ampullary carcinoma. Two of the Whipple's resections had early conversion during dissection because of adjacent visceral invasion requiring extended resections. One Whipple's resection was totally laparoscopic and rest of them required a small incision to complete the anastomosis. The mean operating time was 598 min (425e689). One patient had grade A pancreatic leak that was managed conservatively. The median length of stay was 11 days (6e 22). The median tumour size was 19.3 mm (9e30).The mean lymph node yield was 20 (10e24). There was one case of R1 resection margin because of tumour within 1 mm SMV margin. There were no postoperative mortality. Conclusion: Laparoscopic pancreaticoduodenectomy is feasible and safe in selected group of patients performed by experienced surgeons. The oncological and the short term outcomes are similar to open resections.

Вве де ниеНейроэндокринные опухоли (НЭО) -новообразования из клеток нейроэндокринной дифференцировки, различные по своей биологии и первичной локализации [1]. Стандартизованные показатели заболеваемости НЭО в разных странах варьируют в пределах 0,71-1,36 на 100 000 человек в год. Большинство исследователей отмечают увеличение заболеваемости за последние 30 лет с ежегодным приростом 3% [2]. Частота обнаружения НЭО за последние 10-15 лет увеличилась в 2-3 раза, что объясняется не только улучшением инструментальной и лабораторной диагностики с использованием иммуногистохимических маркеров и электронной микроскопии, но и возможным истинным ростом заболеваемости [3]. НЭО поджелудочной железы (ПЖ) выявляются достаточно редко, примерно 5-10 наблюдений на 1 млн человек в год, и составляют менее 3% от всех новообразований органа [4][5][6]. За последние 15 лет заболеваемость НЭО ПЖ увеличилась в 2-3 раза, в то время как возраст пациентов остается относительно стабильным [5,7]. НЭО ПЖ могут иметь различные