SG + TB is a simple procedure that results in rapid weight loss and remission or major improvement of comorbidities. Strictly aiming at physiological correction, TB avoids prostheses, narrow anastomoses, excluded segments, and malabsorption. Weight and comorbidities are much improved. Diabetes is improved without duodenal exclusion. TB is an excellent complement to an SG.
RESUMOOBJETIVO. Avaliar fatores preditivos de colelitíase em obesos mórbidos submetidos a gastroplastia com reconstrução em Y de Roux. MÉTODOS. Estudou-se um grupo de pacientes obesos inscritos no programa para tratamento cirúrgico da obesidade mórbida do Departamento de Cirurgia da Faculdade de Ciências Médicas da Santa Casa de São Paulo. Os critérios de exclusão foram: pacientes colecistectomizados previamente, pacientes com diagnóstico de colelitíase no pré-operatório e casos em que a ultra-sonografia era duvidosa em relação à presença de cálculos biliares. Foram operados 160 pacientes, sendo 29 com colecistectomia prévia, 23 com litíase biliar pré-peratória, 5 com ultrassonografia duvidosa e 103 com vesícula biliar normal ao ultra-som de abdome. RESULTADOS. Os resultados mostraram que 48 (46,6%) pacientes desenvolveram colelitíase, sendo 22 sintomáticos. Quando comparamos os pacientes com e sem colelitíase, não observamos diferenças significativas em relação à idade, sexo e peso pré-operatório. O índice de massa corpórea, os níveis séricos de triglicérides, o colesterol total e suas frações VLDLcolesterol e LDL-colesterol foram superiores no grupo que desenvolveu colelitíase em relação aos pacientes sem cálculos, sendo esta diferença estatisticamente significativa. A porcentagem de perda de peso no 6º e 12º mês pós-operatório foi significativamente superior nos pacientes que desenvolveram cálculos biliares. CONCLUSÃO. O estudo permite concluir que índice de massa corpórea, os níveis de triglicérides, colesterol total e suas frações LDL e VLDL são fatores preditivos de colelitíase após gastroplastia com reconstrução em Y de Roux. UNITERMOS INTRODUÇÃOA doença biliar é comum nos obesos mórbidos, sendo a obesidade o maior fator de risco para o desenvolvimento de cálculos de colesterol 28 . Cerca de 25% a 45% desta população apresenta colelitíase, sendo realizadas cerca de 750.000 colecistectomias por ano nos Estados Unidos, acarretando um custo de 8 a 10 bilhões de dólares. Quando somadas as colecistectomias prévias e a colelitíase diagnosticada no pré-operatório de obesos submetidos a cirurgia bariátrica esse valor varia de 28% a 45% 1-5 . A alta incidência de doença da vesícula biliar em obesos foi demonstrada por diversos autores, merecendo destaque Dittrick et al. 5 , que compararam doenças da vesícula biliar de obesos submetidos a cirurgia bariátrica e colelistectomia profilática em relação à vesícula biliar de doadores de órgãos. Seus resultados mostraram uma incidência de doença biliar em 79% dos obesos e em apenas 28% do grupo controle 5 . Na Itália, um estudo epidemiológico revelou uma incidência de 17% de cálculos assintomáticos em 4.751 indivíduos submetidos à ultra-sonografia 6 . No Chile, que apresenta a segunda maior prevalência no mundo, estudos realizados após necropsias mostraram que mais de 50% das mulheres adultas tinham colelitíase 7 .Foi evidenciada uma maior incidência de colelitíase em mulheres com IMC maior do que 30 kg/ m 2 do que em mulheres com IMC menor do que 25 kg/ m 2 . Quando est...
BACKGROUND:Various digestive tract procedures effectively improve metabolic syndrome, especially the control of type 2 diabetes mellitus. Very good metabolic results have been shown with vertical gastrectomy and entero-omentectomy; however, the metabolic effects of an isolated entero-omentectomy have not been previously studied.METHODS: Nine patients with type 2 diabetes mellitus and a body mass index ranging from 29 to 34.8 kg/m2 underwent an entero-omentectomy procedure that consisted of an enterectomy of the middle jejunum and exeresis of the major part of the omentum performed through a mini-laparotomy. Glucagon-like peptide-1 and peptide YY were measured preoperatively and three months following the operation. Fasting and postprandial variations in glycemia, insulinemia, triglyceridemia, hemoglobin A1c, and body mass index were determined in the preoperative period and 3, 18 and, 36 months after the operation.RESULTS: All patients significantly improved the control of their type 2 diabetes mellitus. Postprandial secretion of peptide YY and Glucagon-like peptide-1 were enhanced, whereas hemoglobin A1c, fasting and postprandial glucose, insulin, and triglyceride levels were significantly reduced. Mean body mass index was reduced from 31.1 to 27.3 kg/m2. No major surgical or nutritional complications occurred.CONCLUSIONS: Entero-omentectomy is easy and safe to perform. A simple reduction in jejunal extension and visceral fat causes important improvements in the metabolic profile.
Objective Sleeve gastrectomy is the fastest growing surgical procedure to treat obesity in the world but it may cause or worsen gastroesophageal reflux disease. This article originally aimed to describe the addition of anti-reflux procedures (removal of periesophageal fats pads, hiatoplasty, a small plication and fixation of the gastric remnant in position) to the usual sleeve gastrectomy and to report early and late results.Methods Eighty-eight obese patients that also presented symptoms of gastroesophageal reflux disease were submitted to sleeve gastrectomy with anti-reflux procedures. Fifty of them were also submitted to a transit bipartition. The weight loss of these patients was compared to consecutive 360 patients previously submitted to the usual sleeve gastrectomy and to 1,140 submitted to sleeve gastrectomy + transit bipartition. Gastroesophageal reflux disease symptoms were specifically inquired in all anti-reflux sleeve gastrectomy patients and compared to the results of the same questionnaire applied to 50 sleeve gastrectomy patients and 60 sleeve gastrectomy + transit bipartition patients that also presented preoperative symptoms of gastroesophageal reflux disease.Results In terms of weight loss, excess of body mass index loss percentage after anti-reflux sleeve gastrectomy is not inferior to the usual sleeve gastrectomy and anti-reflux sleeve gastrectomy + transit bipartition is not inferior to sleeve gastrectomy + transit bipartition. Anti-reflux sleeve gastrectomy did not add morbidity but significantly diminished gastroesophageal reflux disease symptoms and the use of proton pump inhibitors to treat this condition.Conclusion The addition of anti-reflux procedures, such as hiatoplasty and cardioplication, to the usual sleeve gastrectomy did not add morbidity neither worsened the weight loss but significantly reduced the occurrence of gastroesophageal reflux disease symptoms as well as the use of proton pump inhibitors.
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