The peculiarities of the course of infected pseudoarthroses of the tibia using the extrafocal fixation method are studied, as well as laws of the origin of postoperative complications in this category of patients are revealed. The selection analysis data of patients show the significant discrepancy between the outcome structure and number of postoperative complications and the data given by other authors. At the same time these data on complications correspond or slightly below the data of foreign clinics. Since the data presented are obtained during long-term selection analysis of patients with infected pseudoarthroses treated in specialized clinics they sufficiently show the course of this disease using extrafocal osteosynthesis.

Clinical and histological changes were studied in 96 adolescents with knee pathology of non-traumatic genesis, with signs of connective tissue disease (CTD). The detection of connective tissue dysplasia was carried out according to the data of a clinical examination, functional and radiation diagnostic methods in accordance with the Russian recommendations for algorithms for the diagnosis and treatment of children with connective tissue disease (2015). Serial sections stained with hematoxylin and eosin were examined on an Olympus CX-41 microscope at a magnification of ×100, ×200, ×400. Some of the preparations were additionally stained with picrofuchsin according to van Gieson. Signs of a pronounced diffuse pathological process of a degenerative-dystrophic nature were revealed, caused by hypoxic and metabolic disorders, which led to the development of pain syndrome and became a reason for subsequent surgical intervention.