A steady incompressible chemically reacting fluid between two disks under the influence of cross-diffusion, Hall and ion-slip effects is studied by assuming the lower disk is rotating and the upper disk is stationary. The system of nonlinear differential equations representing velocity, temperature and concentration is solved numerically using spectral quasi-linearisation method. The effects of chemical reaction, Hall current and ion-slip, Dufour and Soret on velocity, temperature and concentration distributions are studied. The stress, rate of heat and mass transfers are discussed for various parameters and the results are displayed in the tabular form. It is found that increasing Hall parameter decreases the temperature and concentration, and the opposite trend observed when ion-slip parameter increased. The concentration reduces with the enhance of the chemical reaction parameter and Soret number.