Canine Distemper (CD) is a severe life threatening disease with a worldwide distribution caused by a Morbillivirus of the family Paramyxoviridae similar to the human Measles virus, transmitted between susceptible hosts and the dog still remains the most important reservoir for the infection (Leisewitz et al., 2001). The disease affects mainly domestic dogs but has become a serious problem in a wide range of hosts, threatening captive and free- ranging wildlife populations including several marine mammals such as seals, dolphins and whales (Visser et al., 1993). Dogs show signs of severe tooth enamel damage or enamel hypoplasia during the course of the disease particularly in young puppies whose teeth have not fully developed