Olive oil contains vitamin E which is a natural antioxidant that is effective to prevent premature aging. The aims of the research was to obtained the most stable gel formulation of polyfloral honey phamaceutically. Physical stability evaluation carried out to in which the parameters were organoleptic, viscosity measurement, homogeneity, spreedability, pH, and flowing type, at 5 o C and 35 o C for 12 hours on each temperature for 10 cycles. Organoleptic assay showed that there was on change in color, odor, and concistency of all formula. Based on statistic analyses by Randomized design exhibited a significant change during storage. Homogeneity test showed that all formula posses even particle distribution. Spreedability test showed that all formula there were changes in viscosity. Based on rheogram exhibited thixotrophy-plastic flow type. From physical evaluation obtained formula B of gel was the must stable (Base gel of HEC). Based on release of active substances formula B of gel (Base gel of HEC) showed the highest release of active substances.

Siam weed leaves are one of the plants that function as wound medicine. This study aims to produce a stable ointment dosage form. Siamese weed leaf extract is formulated in the form of ointment with a variety of bases consisting of a hydrocarbon base, absorption, water soluble and emulsion. Evaluation of physical stability includes organoleptic testing, homogeneity, pH, dispersion, viscosity and flow properties carried out before and after forced conditions. Forced conditions were carried out with stock storage for 10 cycles at 50 and 350. The results of the analysis showed that the viscosity of the preparations in all formulas changed after storage at 50 and 350 for 5 days. However, the statistical results show that all formulas did not experience significant changes between before and after the stress condition treatment.

Palm fruit (Arenga pinnata) contains galactomannan which has the potential as an antioxidant activity with an IC 50 value of 20,45 ppm. This study aims to produce cream dosage forms with antioxidant activity using the scaverry DPPH radical scavenger method from arenga pinnata water extract. Palm fruit water extract is formulated in cream form with variations in the concentration of stearic acid and triethanolamine emulgators in F1 (6:4), F2 (7:3), and F3 (8:2). Evaluation of physical stability includes organoleptic testing, homogeneity, pH, emulsion type, viscosity and type of flow carried out before and after forced conditions. In the statistical analysis of viscosity, the results of each formula showed no significant changes both before and after the conditions were forced. The results of the study obtained formula 2 and formula 3 has optimal stability. The stable formula was then tested for antioxidants using the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) radical scavenger method. Formula 2 and formula 3 each yield a DPPH radical inhibition percentage of 65% and 48.04%.

Objective: Arbenan (Duchesnea indica) plants contain saponins, flavonoids, and tannins which have antioxidant activity. The purpose of this research is to perform formulation and evaluation extract ethanol of Arbenan leaves in the form of serum which is pharmaceutically stable. Method: Arbenan leaf powder was macerated with ethanol solvent, and then left for 3-4 days while stirring repeatedly, and then filtering. Furthermore, the liquid ethanol extract that has been obtained is evaporated using a Rotary Vacum Evaporator was used to evaporate the extract. Prepared extract was used to evaluate various parameters like organoleptics, homogeneity, viscosity, and pH. Result: All formulations were having typical smell, light brown color and a little thick consistency. Formulations of leaf extract of Arabenan with four variations bases have shown to have good stability after stress condition. It can be seen from the evaluation result are organoleptics, homogeneity, viscosity, rheology, and pH. Conclusion: Study concludes that a stable leaf extract of Arabenan can be effectively formulated into a serum by the means of various bases.                                     Peer Review History: Received 8 January 2021; Revised 13 February; Accepted 4 March, Available online 15 March 2021 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Dr. Marwa A. A. Fayed,  University of Sadat City, Egypt, maafayed@gmail.com Prof. Dr. Ali Gamal Ahmed Al-kaf,  Sana'a university, Yemen, alialkaf21@gmail.com Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id Similar Articles: PHYTOCHEMICAL, ANTI-INFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ACUTE TOXICITY OF PSIADIA PUNCTULATA GROWING IN YEMEN ANTIHYPERLIPIDEMIC EFFECT OF THE ETHANOLIC EXTRACT OF SCAEVOLA TACCADA (GAERTN) ROXB. LEAVES ETHNOBOTANY, PHYTOCHEMISTRY AND PHARMACOLOGY OF OCHNA SCHWEINFURTHIANA: A REVIEW

This research was conducted with the aim to investigate the influence of storage on the size of the metal content of Pb and Zn to quality consumable products corned beef cans obtained from a grocery store or supermarket, and to determine the ratio between the metals Pb and Zn results, with SK. DG BPOM No.03725/ B / SK / VII / 89 maximum of metal contamination in food. In this study, the sampling method used is the method of random sampling in which sampling method from a single population and each population has an equal chance to be selected as sample. Analysis of heavy metal Pb in all samples showed uptake results ranged from 0.0000 to 0.0005, or may be heavy metal pollution Pb is very small. Total Pb (lead) was much less after storage in the refrigerator for 1 day of corned beef packaging consumables, it is possible the influence of the storage temperature. Analysis of Zn metal in the samples showed varying results, it is because the meat itself was contained zinc metal content. Total Zn (Zinc) also was less after storage in the refrigerator for 1 day of corned beef packaging consumables, it is possible the influence of storage temperature affect the metal content. Analysis of Pb (lead) and Zn (zinc) in a sample of corned beef canned consumables still below the threshold set by decree. SNI No. 7387:2009 above the maximum limit of metal contamination in food, so the packaging corned beef is still suitable for consumption and circulated in the market.