Êëþ÷åâûå ñëîâà: ëåéêîç êðóïíîãî ðîãàòîãî ñêîòà, âèðóñ ëåéêîçà êðóïíîãî ðîãàòîãî ñêîòà (ÂËÊÐÑ), ãåìàòîëîãè-÷åñêèå è ñåðîëîãè÷åñêèå èññëåäîâàíèÿ, ðåàêöèÿ èììóíîäèôôóçèîííîé ïðåöèïèòàöèè (ÐÈÄ), Ðåñïóáëèêà Äàãåñòàí. Key words: leucosis of cattle, bovine leukemia virus (BLV), hematologic and serologic studies, immunoprecipitation test (AGID), Dagestan Republic. Ðåçþìå. Ëåéêîç êðóïíîãî ðîãàòîãî ñêîòà ñ 1988 ïî 2017 ãã. ðåãèñòðèðóåòñÿ ïðîäîëaeèòåëüíîå âðåìÿ â áîëüøèíñòâå õîçÿéñòâ Ðåñïóáëèêè Äàãåñòàí ñðåäè âñåõ ïîëîâîçðàñòíûõ è ïðîèçâîäñòâåííûõ ãðóïï ñ òåíäåíöèåé ê øèðîêîìó ðàñïðîñòðàíåíèþ. Ïîëó÷åííûå äàííûå ñâèäåòåëüñòâóþò îá îñîáåííîñòÿõ è çàêîíîìåðíîñòÿõ ðàçâèòèÿ è ïðîÿâëåíèÿ èíôåêöèîííîãî è ýïèçîîòè÷åñêîãî ïðîöåññîâ èíôåêöèè âèðóñà ëåéêîçà êðóïíîãî ðîãàòîãî ñêîòà (ÂËÊÐÑ), ÷òî îáóñëàâëèâàåò ñïåöèôèêó ïðîâåäåíèÿ ïðîòèâîëåéêîçíûõ ìåðîïðèÿòèé â ðåñïóáëèêå. Òàê, çà ïîñëåäíèå 9 ëåò îáñëåäîâàíèÿ â ÐÈÄ 8,9 (6,7-12,2) òûñ. ãîëîâ êðóïíîãî ðîãàòîãî ñêîòà åaeåãîäíî âûÿâëÿþò 1,2 (0,4-2,4) òûñ. ïîëîaeèòåëüíî ðåàãèðóþùèõ aeèâîòíûõ, ÷òî ñîñòàâëÿåò 13,5% îò ÷èñëà èññëåäîâàííûõ. Ïîêàçàòåëü èíôèöèðîâàííîñòè åaeåãîäíî ïîääåðaeèâàëñÿ íà óðîâíå 6,5-23,6%. Ãåìàòîëîãè÷åñêèì ìåòîäîì èññëåäîâàëè 246,2 aeèâîòíûõ è ñðåäè íèõ åaeåãîäíî âûÿâëÿëè 78,9 (32,1%) áîëüíûõ. Ëåéêîç êðóïíîãî ðîãàòîãî ñêîòà íàíîñèò ñóùåñòâåííûé ýêîíîìè÷åñêèé óùåðá îòðàñëè è òðåáóåò áîëåå àêòèâíîé è ïåðñïåêòèâíîé áîðüáû ñ ýòèì çàáîëåâàíèåì. Äëÿ ýôôåêòèâíîé ðàáîòû ñ ëåéêîçîì êðóïíîãî ðîãàòîãî ñêîòà íåîáõîäèìî ðàçðàáîòàòü Ðåñïóáëèêàíñêóþ öåëåâóþ ïðîãðàììó. Summary. Leucosis of cattle from 1988 till2017 is registered for a long time in the majority of farms of Dagestan Republic among all age and production groups with a tendency to wide distribution. These results indicate that the features and patterns of development and manifestation of infectious and epizootic processes of virus infection of bovine leukemia (BLV), which determines the specifics of the anti-leukemic activities in the republic. So, during last 9 years of study in AGID 8,9(6,7-12,2) thousands of heads of cattle annually show 1,2 (0,4-2,4) thousands of positively reacting animals, which amounts to 13,5% of the surveyed. The infection rate was maintained on6,5-23,6% each