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Cyanoethylation of lupane triterpenoids was performed. Amide oximes of 3β-O-(2-cyanoethyl)-betulinic acid methyl ester and 3β-O-acetyl-28-O-(2-cyanoethyl)betulin and the corresponding O-[2-(1,2,4-oxadiazol-3-yl)ethyl] lupane derivatives were obtained. * For communication XXIII, see [1].Pentacyclic triterpenoids of the lupane series attract researchers' attention as substrates for synthetic transformations due to their accessibility, as well as due to pharmacological importance of some semisynthetic derivatives which are often available via relatively simple modifications. In the past decade, particular emphasis was put on such pharmacological properties of lupane derivatives as antiviral (HIV-1) and antitumor activity [2]. While developing our studies on the transformations of plant metabolites produced by Sibe-

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