On a farm infectious diseases may occur by introducing infected animals, introduction of cattle in the incubation period, carcasses of animals that were not removed properly, vehicles, equipment, clothing and shoes of visitors or employees who have contact with other herds, more often contact with the herd, contact with other animals (horses, dogs, cats, wildlife, rodents, birds, insects), but also by contaminated objects, contaminated food, and improper management of manure when it comes to the creation of dust and scattering (Hristov, 2007). To prevent introduction of infection to the farm or farms in the environment, we use primary and secondary Biosafety measures. The most effective implementation of biosecurity measures on farms provides a development plan for that farm biosecurity. We have developed the biosecurity plan based on detailed observation and analysis of the relevance of indicators and on biosecurity which includes: 1. Making and submitting a written plan for achieving and maintaining biosecurity on farm production based on keeping proper records; 2. Isolation of he farm as a whole or individual segments of manufacturing and production operations; 3. Introduction of newly acquired animals in a herd; 4. Health of the herd; 5. Evaluations of the personnel and the equipment; 6. Traffic and movement control; 7. Attitude towards visitors; 8. Control of food and water; 9. Manure; 10. Disposal of carcasses of dead animals; 11. Relationship to other animals on the farm; 12. Population control of rodents and birds; 13. Sanitation (Stanković et al,, 2010).

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