The present research had the purpose to analyze morphologically the sites of endometrial implants on the external area of the musculature of the anterior abdominal wall of female rats, treated with dexamethasone. For so, these 15 albino female rats were used (Rattus norvegicus albinus), of the lineage Wistar with 90 days of age, that were submitted to the induction of the endometriosis, and divided in the following groups: Group I-induced female rats to endometriosis and evaluated after 21 days (control); Group IIinduced female rats to endometriosis and after 21 days, treated with dexamethasone for 10 days; Group III-induced female rats to endometriosis, and after 21 days, treated with dexamethasone for 15 days. The dexamethasone was administered in the dosage of 0,8 mg/ day/animal. Our results showed that the chronic inflammatory process in the endometriosis doesn't decrease after treatment with dexamethasone for 10 days, while the treatment with dexamethasone for 15 days reverted the chronic inflammatory process in the endometriosis, besides stimulating the proliferation of glands in endometrial implants.
RESUMO A presente pesquisa teve como objetivo analisar morfologicamente os sítios de implantes endometriais sobre a região externa da musculatura da parede abdominal anterior de ratas, durante o ciclo estral. Para tanto foram utilizadas 16 ratas albinas (Rattus norvegicus albinus), da linhagem Wistar com 90 dias de idade, obtidas do biotério do Departamento de Morfologia e Fisiologia Animal da UFRPE, as quais foram submetidas à indução da endometriose. A análise histológica dos implantes foi realizada por meio da microscopia de luz, utilizando-se técnicas de colorações pela Hematoxilina-Eosina (H-E) e pelo Tricrômico de Mallory. O material coletado foi fixado em líquido de Boüin e processado para inclusão em “paraplast”. Os resultados mostraram que as fases de proestro, estro e diestro foram mais favoráveis para o desenvolvimento dos implantes endometriais em ratas, quando comparadas ao metaestro.
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