The present research had the purpose to analyze morphologically the sites of endometrial implants on the external area of the musculature of the anterior abdominal wall of female rats, treated with dexamethasone. For so, these 15 albino female rats were used (Rattus norvegicus albinus), of the lineage Wistar with 90 days of age, that were submitted to the induction of the endometriosis, and divided in the following groups: Group I-induced female rats to endometriosis and evaluated after 21 days (control); Group IIinduced female rats to endometriosis and after 21 days, treated with dexamethasone for 10 days; Group III-induced female rats to endometriosis, and after 21 days, treated with dexamethasone for 15 days. The dexamethasone was administered in the dosage of 0,8 mg/ day/animal. Our results showed that the chronic inflammatory process in the endometriosis doesn't decrease after treatment with dexamethasone for 10 days, while the treatment with dexamethasone for 15 days reverted the chronic inflammatory process in the endometriosis, besides stimulating the proliferation of glands in endometrial implants.

The glucocorticoid dexamethasone has been largely used due to its anti-inflammatory effect. However, several authors report that the excessive exposition to it during pregnancy may cause a retard in the development in several tissues, mainly: liver, lungs and kidneys. But, the majority of the works are done with the application of dexamethasone in the late periods of pregnancy. Because of the lack of researches that evaluate the effects in the beginning of gestation, this paper aimed at evaluating the effect of dexamethasone administered in the initial phase of pregnancy, over the morphology of neonates rat. It was used 10 albino rats (Rattus norvegicus albinus) aged 90 days from the lineage Wistar. The female were coupled and divided in two groups: Group I -rats not submitted to the dexamethasone application (control); Group II -rats submitted to the dexamethasone application in the first 5 days of pregnancy. The results show that the treatment with dexamethasone in a dosage of 0.8mg/Kg during the 5 first days of pregnancy does not produces a weight and height reduction or malformation in the offspring, it does not cause changes in the development of the liver and kidneys of neonate rats, but it leads to a reduction in the denseness of the interalveolar septa causing a higher distension of the alveoli.

A população de raças caprinas naturalizadas e Sem Raça Definida (SRD) do Nordeste do Brasil é pouco caracterizada, apesar da importância que se tem dado aos estudos de recursos genéticos em animais domésticos. Com o objetivo de estudar o polimorfismo do gene da αS1-caseína em DNA genômico de cabras Moxotó e SRD provenientes do Semiárido do Nordeste brasileiro, por meio da técnica de PCR-RFLP (Polymerase Chain Reaction-Restriction Fragment Lenght Polymorfism), foram genotipadas 215 cabras pertencentes aos grupos genéticos Moxotó e SRD, provenientes dos estados de Pernambuco, Paraíba, Rio Grande do Norte e Ceará. Com base na frequência alélica das raças estudadas, não se observou diferença significativa (p> 0,05) entre as populações de cada Estado e entre animais Moxotó e SRD. Diante da maior frequência observada do alelo B (forte) do gene da αS1-caseína nos animais estudados, admite-se a possibilidade de que fenotipicamente esses animais venham a exibir a característica de uma forte produção de proteínas, característica importante para o leite destinado à produção de queijos, favorecendo a caprinocultura da região.

SUMMARY:The present study had the objective of obtaining information about fertility in rats treated with dexamethasone for 10 and 15 days consecutively, to polycystic ovaries, induced by constant illumination. It was used 40 albino rats (Rattus norvegicus albinus), aged 90 days, form the lineage Wistar, which were split, randomly, in four groups, each constituted of 10 animals, namely: Group I -rats kept in a clear/dark cycle for 12/12 hours, and after 100 days submitted to fertility evaluation (control); Group II -rats kept under constant illumination during 100 days and then submitted to fertility evaluation; Group III -rats kept under constant illumination during 100 days, then treated with dexamethasone for 10 days and submitted to fertility evaluation; Group IV -rats kept under constant illumination during 100 days, then treated with dexamethasone for 15 days and submitted to fertility evaluation. The results showed that the number of implanted sites was 38(G1), 37(G2), 32(G3) and 06(G4). The reduction in group IV was due to the high mortality during the experiment, probably because of the prolonged treatment with dexamethasone. These sites presented similar histological aspects. The macroscopic analysis of the neonates haven't shown any indication of malformation. Also, abortion haven't been observed. The treatment with dexamethasone for 10 days in rats does not affect the fertility and the development of the lungs, liver and kidneys of neonates, while the administration during 15 days leads to a high maternal mortality.