The present study was carried out to evaluate the effects of exposure at different doses of acephate on hematology, blood biochemistry, oxidative stress and immune system of Wistar rats. The experiment was carried out on 40 Wistar rats, which were divided in four groups. Animals of the three treatment groups were given with different sublethal doses (1/40th, 1/20th, 1/10th of lethal dose 50 value) of acephate by oral gavage. The hematology, blood biochemistry, oxidative stress marker, humoral immune response and cell-mediated immunity were evaluated following acephate exposure. Significant alteration in hematological parameters was not observed following different doses of acephate; however, significant alteration in alkaline phosphatase, gamma glutamyl transferase, acetyl cholinesterase, lipid peroxidase and superoxide dismutase was observed in medium- and high-dose group animals. Nonsignificant decrease in antibody titer in animals exposed to high dose has been observed compared with animals of control group. However, significant alteration in cell-mediated immunity was not observed in animals treated with acephate at different doses.
Aim:The objective of an experiment was conducted to evaluate the effect of feeding bypass Methonine-Lysine on hematological and biochemical parameters on growing Jaffrabadi heifers of age from 12 to 18 month.
Material and Methods:Eighteen Jaffrabadi heifers were divided into three groups of equal number: control group (T ), and biochemical parameters like total protein, albumin, globulin, creatinine and creatine kinase.
Conclusion:Bypass Methionine and Lysine have no effect on hematological and biochemical parameters except blood urea nitrogen (BUN) in growing Jaffrabadi heifers.
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