Summary Erythema nodosum occurs more frequently than pyoderma gangrenosum in Crohn’s disease. We report the occurrence of both lesions in a woman with Crohn’s disease and the transformation of one to the other. Pyoderma gangrenosum has been described at the site of previous trauma in Crohn’s disease and at the site of other skin conditions in other circumstances, but, to the best of our knowledge, actual progression from erythema nodosum to pyoderma gangrenosum has been reported on only one previous occasion in Crohn’s disease.

BRITISH MEDICAL JOURNAL VOLUME 289 21 JULY 1984 159 between infarction and haemorrhage in the three groups is essentially unchanged. That treatment has different effects on different lesions caused by hypertension is perhaps not surprising. The most probable explanation is that the processes giving rise to atheroma are already established at the time when treatment is begun and that progression of these processes is unaffected by treatment. If so, preventive methods may require earlier intervention even before drug treatment would normally be considered. Further studies of possible reversible environmental factors in hypertension are required to define how practicable such measures are, but the burden of cerebrovascular disease in an aging population demands that these problems be examined scientifically.

No abstract

No abstract