Arista is a classical Ayurvedic preparation that is typically used as a digestive and cardiotonic. The present Investigation evaluated five different brands of Dasamoolaristam available in the market as per WHO and Indian Pharmacopoeial specifications. Various physicochemical parameters such as alcohol-soluble extractive, water-soluble extractive, total ash, acid-insoluble ash, total solid, and alcohol content were determined. The present investigation reveals that all the preparations contain acceptable levels of alcohol (less than 12% v/v). However, the preparations were found to contain unacceptable limits of microbial load although all showed the absence of Escherichia coli, Salmonella species, and Staphylococcus aureus.
The antidiarrheal activity of the methanolic extract of the leaves of Capparis zeylanica (Capparidaceae) was investigated by castor oil-induced diarrhea and small intestine transit method on mice. Like loperamide (3 mg/kg body weight), C. zeylanica methanolic extract (100,150,200 mg/kg body weight) produced a significant decrease in the severity of diarrhea. The percentage protection in extract-treated animals showing diarrhea was compared with castor oil-treated and loperamide-treated animals. The activity was found to be dose-dependant. Its effect when evaluated on intestinal transit produced a decrease in intestinal transit (75.97%).The results revealed that the methanolic extract significantly reduced diarrhea in mice with reduction in weight of stools.
Pet ether and acetone extracts of the plant Aristolochia Bracteata were prepared using Soxlet extraction. phytochemical analysis of Aristolochia Bracteata showed the presence of alkaloids, carbohydrates, flavones, triterpenoids and phytosterols in the crude extracts. In the present study, Pet.ether and acetone extracts of Aristolochia Bracteata was investigated for their anti pyretic activity. Injection of 20 ml/kg (s.c) of 20% aqueous suspension of Brewer's yeast suspension produced pyrexia in rats. Extracts at 250 mg/kg exhibited significant anti pyretic activity. Aspirin (300mg/kg) was included as standard. Pet. Ether extracts was found to be more effective than acetone extract.
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