Despite a significant range of therapeutic measures employed to treat inflammatory diseases in the maxillofacial area, much of the effort falls short of effective suppression of the infection and proper regeneration as the outcome of the pathological process [1-6]. The development of optimal wound covering that would contribute to fast and complete recovery of the damaged structures appears an urgent issue in modern medicine. Scientific items, monographs and patents offer a wide range of materials used to create wound covering, with over 400 various types of sponges, films, combined collagen/gelatin/oxidized cellulose/starch-based implants, etc., described nowadays [7-10]. Of the well-known new-generation biodegradable synthetic and natural materials, a special place A B S T R A C T-A promising area in dentistry is the development of modern biotechnological wound dressings based on chitosan, which, depending on the molecular weight and three-dimensional structure, is able to change its physicomechanical properties from the state of a hydrogel to a dense frame structure with a different degree of swelling, and at the same time perform a depot function the drug introduced into it. Two new types of wound dressings based on chitosan with an immobilized 10% aqueous solution of iodopyrone were developed and their effectiveness was studied in an experiment on animals (rabbits) for dental practice. A comparative analysis was carried out with the well-known wound dressings Alvostaz, Gelatamp by introducing the studied samples into the well of the tooth after its extraction. The high efficiency of the proposed wound dressings based on chitosan was established.

The problem of treating wounds of various origins remains one of the most urgent. Working with a wound defect is one of the main components of the healing process, due to the need to find the most effective methods for treating wounds and caring for them.Due to the COVID-19 pandemic, limited access of students to health care facilities makes it impossible or difficult to teach local wound healing skills in real patients. Under these conditions, one of the options for solving this problem is the use of experimental biological models for practical training.