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Within the frame of a project on biologically active organometallic compounds twenty five triorganotin and organogermanium carboxylates of the type R 3 M0C(0)CH(0X)Ph (M = Sn, Ge; R = Me, Et, n-Bu; X = H, Me, C(0)Me, C(0)CF 3 , R 3 Ge), several diorganotin carboxylates R 2 Sn[0C(0)CH(0X)Ph] 2 (R = Et, n-Bu; X = Me, C(0)Me and {[R 2 Sn0C(0)CH(0X)Ph] 2 0} 2 (R = Et, n-Bu; X = Me, C(O)Me) and a new type of triorganogermanium carboxylates R 3 GeC^CCH 2 0C(0)CH(0X)R' (R = Me, Et, R' = Ph, Me, X = COCH 3 , COCF 3 ) have been synthesized and characterized by elemental analysis and structural methods (NMR, X-Ray, IR and Mössbauer). Introduction.Organotin and organogermanium compounds are the subject of special interest as potential antitumor agents. The literature analysis shows that antitumor activity is mostly characteristic of the covalent compounds of germanium and tin, in which the fragments forming the intra-and intermolecular coordination bonds with germanium and tin atoms do exist.The organotin and organogermanium carboxylates are of this type. The new organogermanium and organotin derivatives of α-substituted phenylacetic acids are described in this paper. Because of the specific properties of organotin and organogermanium carboxylates we will first describe the germanium compounds, and, afterwards, the derivatives of tin.

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Acetylenic metalorganic compounds, prepared in situ from the alkyl ethynyl ethers (I), are coupled with the haloboronic amides (II) or trimethyl borate (IV) to give the alkoxyethynylboronic acid amides (III) and esters (V) respectively.

2002 organo-silicon compounds organo-silicon compounds S 0060 06 -190 Silylation and Germylation of Trialkylsilyl(germyl)ethoxyacetylenes Containing Bulky Substituents at the Silicon or Germanium Atom -[formation of bis-organoelement-containing ketenes [cf. (V), (VII)] as the only reaction products]. -(PONOMAREV, S. V.; ZOLOTAREVA, A. S.; LEONT'EV, A. S.; KUZNETSOV, YU. V.; PETROSYAN, V. S.; Russ. Chem.