The results of a study conducted on 50 knees endoscopically reconstructed for an anterior cruciate ligament (ACL) lesion with a free bone-patellar tendon-bone graft and 9 cadaver knees are reported. The mean lengths of the patellar tendon (45.48 +/- 4.71 mm) and intra-articular ACL graft (20.44 +/- 1.98 mm) were measured in the operated knees. The mean length of the tibial bone tunnel (51.62 +/- 2.60 mm) was also measured with a tibial guide at 55 degrees. No statistically significant correlation was found between these three measurements. The length of the patellar tendon was weakly correlated with body height. Measurement of the tibial tunnel on the cadaver knees with increasing degrees of inclination revealed a mean length increase of 0.68 mm per degree (confidence limits: 0.49-0.86). Comparison between the tunnel lengths obtained with the guide and those measured with a Kirschner wire showed a mean difference of 2.3 mm. It is thus desirable to make the tunnel about 53 mm long to ensure excellent fixation of a 28 mm bone block with a 25 mm interference screw. Correct measurement of the anatomical structures involved is in any event an essential requirement for proper execution of the surgical technique.

Cartilage defects represent a common problem in orthopaedic practice. The knee is frequently involved and the medial femoral condyle is the most common localization. Predisposing factors are: traumas, inflammatory conditions and biomechanics alterations. Several surgical options are available once correct diagnosis is given and accurate patient evaluation has been performed. The aim of our study was to prospectively evaluate functional results of modified autologous matrix induced chondrogenesis (AMIC) technique in a population of patients affected by focal cartilage defects A population of 17 patients was enrolled in this study. 10 patients were male, mean age at the time of surgery was 39 years, right side was involved in 11 cases. All patients were evaluated with accurate physical exam and complete imaging study. At an average FU of 36 months, mean IKDC score and Lysholm score improved from 32 to 82 and from 38 to 74.13 patients out of 17 (76.5%) were satisfied or extremely satisfied with their functional result. MRI control showed reduction of the defect area and subchondral oedema in 10 cases (58.8%). AMIC technique is a relatively new option in the treatment of full thickness cartilage lesions. It enhances the advantages of microfractures since the Chondrogide membrane protects and stabilizes the blood plug acting as a matrix for new cartilage formation. First reports on AMIC technique, show comparable results to autologous chondrocyte implantation (ACI) with the advantage of a single stage technique and no donor site morbidity. AMIC technique represents a new option in the treatment of full thickness cartilage defect. It is safe and reliable. Our data are in accordance with previously reported series in literature and confirm the good objective and subjective results of this procedure.

No abstract

The bone-ligament junction is one of the most complex biological tissues. Its key function is distribution of mechanical loads applied to the ligament in such a way as to diminish the concentration of stresses or shearing at the interface. This paper reports an experimental assessment of the extent to which a nearly normal junction is formed following reconstruction of the anterior cruciate ligament (ACL) with patellar tendon in 20 New Zealand white rabbits sacrificed after 2-38 weeks. A histological comparison was also made with cadaver ACLs. After 5 weeks the new ligament was still separate from the tunnel wall, inflammation was no longer present, and there was no junction tissue. A thin fibrocartilage layer was observed between the bone and the ligament after 12 weeks and was thicker 6 weeks later. After 28 weeks, there was a substantial layer of fibrocartilage. The new junction was virtually "physiological" by the 38th week, with all four layers present. Many fibrocartilaginous cells were also visible between the collagen fibres. The bone-ligament insertion was almost normal. These findings indicate that tendon reconstruction results in the formation of a structure very similar to a physiological junction, and thus ensures better load distribution over a greater ligament insertion area.

Purpose Periprosthetic joint infections (PJIs) represent a devastating consequence of total joint arthroplasty. The European Knee Associates (EKA), the American Association of Hip and Knee Surgeons (AAHKS) International Committee, and the Arthroplasty Society in Asia (ASIA) board members were interested in quantifying diferences in arthroplasty surgeons' use of various PJI prevention measures to provide clinical recommendations to reduce PJI incidence. Methods A prospective Microsoft Forms online survey was distributed among EKA, AAHKS International Committee, and ASIA members and their ailiated arthroplasty surgeons. The survey consisted of 20 single and multiple response questions focused on PJI prevention strategies at three perioperative periods: preoperatively, intraoperatively, and postoperatively. Results Three hundred and ninety-four arthroplasty surgeons from 6 diferent continents completed the survey. Preoperative: (A) PJI Risk Stratiication: 40.6% routinely set thresholds (e.g., BMI, HgbA1C) to be met to qualify for surgery, 36.5% only review past medical history; 9.1% use machine learning to personalize PJI risk; (B) BMI limit: 36% no limit; 15.4% BMI < 35; 30.9% BMI < 40; 17.2% BMI < 45; (C) Nutritional status: 55.3% do not screen; among those who screen their patients (44.7%), albumin is the single most used marker (86.3%); (D) Hyperglycemia/Diabetes: 83.3% check this comorbidity; 88.1% use HgbA1C as single best screening test; (E) MRSA nasal colonization: 63.7% do not test; 28.9% test all patients; 7.4% test selectively. Intraoperative: (A) Antibiotic prophylaxis in high-risk patients: 43.4% use single antibiotic for 24 h; 21.3% use double antibiotic for 24 h; 14.2% use single/double antibiotic for 7 days postoperatively; (B) Skin-cleansing: 68.7% at home (45.6% chlorhexidine sponge; 11.9% clippers); (C) Intraoperative skin disinfection: 46.9% single chlorhexidine; 25% double chlorhexidine-povidone-iodine;15.4% single povidone-iodine; (D) Tranexamic acid (TXA) to reduce bleeding/SSI: 96% yes (51% double IV dose, 35.2% single IV dose, 23.6% intra-articular injection); (E) Surgical suction drain: 52% do not use drains; 19.7% use a drain < 24 h; (F) Intra-articular lavage: 64.9% use only saline; 28.1% use dilute povidone-iodine; (G) Antibiotic local delivery to prevent PJI: 82.4% use antibiotic-added cement. Postoperative: (A) Routine monitoring of PJI serologic markers: 42% only in symptomatic patients; 34.2% do not; 20.8% in all patients; (B) Serologic markers to rule in/out PJI: 95.9% CRP; 71% SEDRATE; 60.6% WBC; (C) Synovial luid test to rule in/out PJI: 79.6% culture/sensitivity; 69.5% WBC count; 31.4% CRP.Conclusions This survey demonstrated that notable diferences still exist in the application of PJI preventive measures across diferent geographic areas: Optimizing the patient preoperatively and applying multimodal intraoperative strategies represent newer, clinically relevant steps in the efort to reduce the burden of PJI. More uniform guidelines still need to be produced from international sc...