2011
DOI: 10.1177/03946320110241s228
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The Manangement of Knee Cartilage Defects with Modified Amic Technique: Preliminary Results

Abstract: Cartilage defects represent a common problem in orthopaedic practice. The knee is frequently involved and the medial femoral condyle is the most common localization. Predisposing factors are: traumas, inflammatory conditions and biomechanics alterations. Several surgical options are available once correct diagnosis is given and accurate patient evaluation has been performed. The aim of our study was to prospectively evaluate functional results of modified autologous matrix induced chondrogenesis (AMIC) techniq… Show more

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Cited by 38 publications
(29 citation statements)
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“…Similar results were found in a larger multicentre observational study including 57 patients 2/3 3 2 2 5 1 3 5 1 1 >2/3 5 2 2 9 10 4 6 8 6 not evaluable 0 0 0 1 0 0 0 0 0 Surface largely uneven 4 3 5 2 2 4 4 3 3 partially uneven 4 1 3 11 6 3 6 4 4 smooth 3 3 0 2 6 2 2 4 1 not evaluable 0 0 1 1 1 2 2 3 4 Integration marginal gap up to 50% ® using Pridie perforations instead of MFx, assessed up to 36 months with significant improvement in clinical scores and reduction of the defect area [24]. Similar results were shown for 17 patients with a larger mean defect size and 76% of the patients were satisfied or extremely satisfied [25]. Kusano et al evaluated outcomes of 38 patients treated with AMIC ® for full-thickness chondral and osteochondral defects of the femoral condyles and patella [26].…”
Section: Amicmentioning
confidence: 65%
“…Similar results were found in a larger multicentre observational study including 57 patients 2/3 3 2 2 5 1 3 5 1 1 >2/3 5 2 2 9 10 4 6 8 6 not evaluable 0 0 0 1 0 0 0 0 0 Surface largely uneven 4 3 5 2 2 4 4 3 3 partially uneven 4 1 3 11 6 3 6 4 4 smooth 3 3 0 2 6 2 2 4 1 not evaluable 0 0 1 1 1 2 2 3 4 Integration marginal gap up to 50% ® using Pridie perforations instead of MFx, assessed up to 36 months with significant improvement in clinical scores and reduction of the defect area [24]. Similar results were shown for 17 patients with a larger mean defect size and 76% of the patients were satisfied or extremely satisfied [25]. Kusano et al evaluated outcomes of 38 patients treated with AMIC ® for full-thickness chondral and osteochondral defects of the femoral condyles and patella [26].…”
Section: Amicmentioning
confidence: 65%
“…A recent prospective study with 17 patients and a 36-month follow-up reports an improvement of the Lysholm score from preoperative 38 to 74 at follow-up [31]. 76.5 % of the patients were satisfied or extremely satisfied with their functional results [31].…”
Section: Discussionmentioning
confidence: 97%
“…Although AMIC is a well-established treatment in cartilage defect therapy, only sparse published evidence is found in the literature [16,24,31]. In a follow-up trial on 27 patients treated with AMIC in its original form, a significant improvement of all clinical scores was seen and 87 % of the patients were highly satisfied with the results after surgery [16].…”
Section: Discussionmentioning
confidence: 99%
“…The hypothesis was that the positive short-term outcomes achieved in the previous series [20] would not deteriorate at a 7-year follow-up.…”
Section: Introductionmentioning
confidence: 99%