Skin temperature was monitored during a graded exercise to verify whether trained individuals have different skin thermoregulation from untrained ones. Eighteen subjects (10 trained; 8 untrained) were studied recording thermal videos of their skin temperature during the exercise. Training level was assessed by maximal oxygen uptake measurements. Trained individuals have better skin thermal control than untrained.

Systemic Sclerosis is a connective tissue disorder featuring vascular alterations and an immunological activation leading to a progressive and widespread fibrosis of several organs such as the skin, lung, gastrointestinal tract, heart and kidney. Moreover men with systemic sclerosis (SSc) present an increased risk of developing erectile dysfunction (ED). Recently, we evaluated the extent of penile vascular damage in sclerodermic patients using Duplex ultrasonography. The aim of this paper is to investigate whether penile thermal differences exist between sclerodermic patients and healthy controls. For this reason 10 men with SSc receiving current treatment for their disease, and 10 healthy controls were enroled; penile thermal properties were assessed through non-contact thermal imaging (functional Infra Red Imaging flRI); erectile function was evaluated using the sexual health inventory for men (SHIM) questionnaire. The SHIM results confirmed the presence of ED in sclerodermic patients. Baseline penile temperature in patients (32.1 ± 1.4°C) was lower than in controls (34.1 ± 0.9°C). Recovery from cooling test was seen to be faster in healthy controls than in patients, both in terms of recovery amplitude (patients 3.75 ± 2.09°C, controls 9.80 ± 2.77°C) and amplitude to time constant ratio (patients 1.21 ± 0.64°C/min, controls 1.96 ± 0.48°C/min). These results show that penile thermal abnormalities occur in almost all sclerodermic patients. Non-contact thermal imaging not only identifies thermal alterations but also clearly distinguishes between SSc patients and healthy controls and therefore could represent a valuable instrument in identifying early ED in SSc patients.

Functional infrared imaging has been used to study 17 patients, affected by myofascial pain, and 19 healthy subjects during maximal voluntary clenching (MCV). Aim of the study was to attempt to discriminate patients from healthy subjects through the analysis of the skin temperature distribution and its change during the clenching. The prestress and the post-stress temperatures were evaluated bilaterally for several regions of interest. We calculated differences in temperature between sides (DeltaTs) at each time (pre and post), and between times (DeltaTt) for each side (left and right). Subsequently, we compared DeltaTs and DeltaTt between the healthy and myofascial pain groups. DeltaTs was significantly higher in sufferers compared to healthy people (p<0.05) for both types of evaluation (by side and by time). DeltaTs was significantly different for masseter and sternocleidomastoid, whereas DeltaTt was higher in almost all sites (masseter, sternocleidomastoid, cervical and upper trapezius). Healthy subjects, undergoing MVC, showed the lowest DeltaT value variability, suggesting that temperature remained constant despite the induced physical exercise. Functional infrared imaging seems to distinguish healthy subjects from the patients suffering myofascial pain in almost all the investigated sites.

Biomedical protocols based on thermal infrared images often require effective image registration. Algorithms specifically designed for registration of thermal images are hardly available and use of algorithms designed for other imaging techniques may result poorly reliable. In fact, registration algorithms developed for other biomedical images often require rigid-body assumption or limited range for intensity values. Such assumption may not be applicable for human body thermal images. Therefore, we present here an adaptation of a field-warp based method as a possible solution for thermal image registration. The method was applied for registering images taken from an experimental protocol aimed at comparing total body skin temperature distribution in natural or altered posture. The method appears to be effective into providing a reliable tool for objective intra and inter individual skin temperature distribution comparisons.

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