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Improvement of methods of treatment of odontogenic cysts of the jaws continues to be an urgent problem in surgical dentistry and maxillofacial surgery. Currently, the most promising is the use of multicomponent osteoplastic materials in order to optimize reparative osteogenesis after cystectomy for extensive jaw cysts. The aim of the study is to improve the method of cystectomy in the surgical treatment of large cysts of the upper jaw with osteoplasty of the bone defect with biocomposite materials in combination with the method of directed tissue regeneration. Clinical, radiological, histological. During the period 2015-2019, 54 patients with odontogenic cysts of the jaws were under observation, of which 12 were diagnosed as extensive. After cystectomy, the bone cavity was filled with biocomposite material: hydroxylappatite granules (Polistom, RF) in combination with PRP, on top of an autoplasma membrane isolated from PRP and collagen membrane. The immediate and long-term periods of treatment were quite favorable. Control X-ray examination after 12 months showed complete recovery of the bone defect with an organotypic structure in all patients.

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