One of the main problems of the Far East of Russia is a tendency of long-term reduction of the population of the region. While maintaining natural loss, there is an outflow of labor resources in the central part of Russia. In this situation, it is advisable to refer to a historical experience of state policy on replenishing the region with labor. The paper focuses on a comprehensive study of the activities of government agencies on the implementation of agricultural family relocation policies from the central part of Russia to the Far East. The reasons for family relocations, contributing to an increase in the population of the region, are substantiated. Some features of the organization of the process of resettlement and adaptation of the families of agricultural migrants in the 20s and 30s of the 20th century are considered. The findings on the economic and social-legal regulation of family relocations in the 20s and 30s of the 20th century can be used in the development of federal and regional programs to consolidate the population in the Far East of the country.