Given the most frequent manifestation of psoriasis at a young working age and in some cases severe, continuously recurrent course, the presence of many treatments, none of which is a guarantee of complete recovery and no recurrence – now there is an urgent need to find prognostic signs therapy and prevention of relapses. In the absence of ideal biomarkers, the study of constitutional markers becomes crucial. The aim of the study was to examine the differences in girth body sizes between healthy and/or psoriatic men depending on the severity of the disease. Anthropometric examination according to V.V. Bunak was performed for 32 men of the first mature age patients with mild and 68 with severe psoriasis course. The PASI index was used to clinically assess the severity and area of psoriatic lesions. The control group, according to anthropometric parameters, consisted of 82 practically healthy men of the same age, selected from the database of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. In patients with psoriasis of mild and severe course, compared with healthy, we found: greater values for – the girth of the shoulder in a tense state by 8.9% and 6.8%; shoulder girth in the unstressed state by 14.2% and 12.3%; forearm girth in the upper part by 8.0% and 7.1%; forearm girth in the lower part by 4.2% and 4.5%; hand girth by 5.1% and 5.8%; hip girth by 11.4% and 9.3%; hips circumference by 8.7% and 6.5%; crus girth in the upper part by 10.2% and 7.9%; crus girth in the lower part by 8.7% and 5.9%; neck girth by 6.9% and 7.8%; waist circumference by 17.1% and 18.2%; chest girth on inspiration by 7.8% and 7.2%; chest girth on exhalation by 10.6% and 10.3%; chest circumference at rest by 10.0% and 9.6%. Thus, there are pronounced differences in the girth sizes between healthy and patients with mild and severe psoriasis Ukrainian men of the first mature age. Between patients with varying degrees of severity of dermatosis, differences are established only for the girth of the crus in the lower part.