A ventricular septal defect is the most common congenital heart disease. With the improvement of cardiac surgery, the survival rates of children with heart disease have improved. In addition to clinical and hemodynamic improvement, an important task is to study the perception of the quality of life of children with an interventricular septal defect. The purpose of the study is to compare the quality of life of children with a ventricular septal defect. Materials and methods of the study: a survey was conducted of children with ventricular septal defect 3-17 years old (median age 9 years (Q1-Q3 - 5-12 years), as well as their parents using the Russian-language version of the international tool Pediatric Quality of Life Inventory (PEDsQL) 3.0 Cardiac Module used to assess the quality of life of children with diseases of the cardiovascular system. Results: the quality of life on the “heart problems” scale in children operated on for an interventricular septal defect was significantly lower than in children without surgical defect correction. In patients with FC | and || (n = 14) according to NYHA and Ross, the quality of life was statistically significantly lower on the scales “heart problems”, “anxiety associated with treatment”, “learning problems” than in patients with FC 0 (p <0.05). The quality of life of children with a body mass index below the norm on the “heart problems” scale was significantly lower than in children with a body mass index higher and within the norm (p <0.05). Conclusions: the quality of life of children with a ventricular septal defect may be impaired. Nevertheless, children without operational correction, with normal and above normal levels of physical development, in the absence of heart failure, better perceive the quality of life. In order to provide high-quality care, in addition to a thorough clinical assessment, quality of life should be an important aspect of the comprehensive treatment of heart disease

The aim of the study was to assess heart rate variability in children with a ventricular septal defect (VSD). Material and methods: Holter monitoring was performed in patients with ventricular septal defect from 3 to 18 years of age with an assessment of the temporal and spectral parameters of heart rate variability. Conclusion: in children with VSD, a decrease in the parameters of the temporal analysis of heart rate variability compared with healthy peers (p <0.05) was observed, more pronounced in patients with operative correction of the defect, as well as an increase in the low-frequency spectrum power (LF) as an indicator of amplification sympathetic effects on heart rate. A statistically significant correlation was found between the SDNN, SDANNi parameters and the pressure levels in the right ventricle and pulmonary artery (ρ = 0.5, p <0.01) in the group of patients with benign VSD without operative correction of the defect. The decrease in indicators of the temporal parameters of heart rate variability was inversely correlated with an increase in the postoperative period. Conclusions: in children who underwent surgical closure of the VSD, there was a disturbed heart rate variability, which had an inverse correlation with the duration of the postoperative period