Purpose: To formulate hydrogels based on poloxamer 407 and polyacrylic acids (Carbopols® 971P and 974P), and evaluate its suitability for enhanced topical delivery of gentamicin, a potent but highly toxic aminoglycoside antibiotic. Methods: Topical hydrogels of gentamicin were produced using poloxamer 407 and polyacrlic acids (Carbopols® 971P and 974P)
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