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Three-dimensional Digital Image Correlation (3D-DIC) is a non-contact optical-numerical technique for evaluating the dynamic mechanical behavior at the surface of structures and materials, including biological tissues. 3D-DIC can be used to extract shape and full-?eld displacements and strains with high resolution, at various length scales. While various commercial and academic 3D-DIC software exist, the field lacks 3D-DIC packages which offer straightforward calibration and data-merging solutions for multi-view analysis, which is particularly desirable in biomedical applications. To address these limitations, we present MultiDIC, an open-source MATLAB toolbox, featuring the first 3D-DIC software specifically dedicated to multi-view setups. MultiDIC integrates robust two-dimensional subset-based DIC software with specially tailored calibration procedures, to reconstruct the dynamic behavior of surfaces from multiple stereo-pairs. MultiDIC contains novel algorithms to automatically merge meshes from multiple stereopairs, and to compute and visualize 3D shape and full-?eld motion, deformation, and strain. User interfaces provide capabilities to perform 3D-DIC analyses without interacting with MATLAB syntax, while standalone functions also allow proficient MATLAB users to write custom scripts for specific experimental requirements. This paper discusses the challenges underlying multi-view 3D-DIC, details the proposed solutions, and describes the algorithms implemented in MultiDIC. The performance of MultiDIC is tested using a low-cost experimental system featuring a 360-deg 12-camera setup. The software and system are evaluated using measurement of a cylindrical object with known geometry subjected to rigid body motion and measurement of the lower limb of a human subject. The findings confirm that shape, motion, and full-field deformations and strains can be accurately measured, and demonstrate the feasibility of MultiDIC in multi-view in-vivo biomedical applications.