Background Pulmonary carcinoids are included in the group of neuroendocrine tumors (NET) and derive from pulmonary neuroendocrine cells. The incidence of these tumors is increasing, but disease awareness remains low among clinicians. The synchronous presentation of lung cancer and mycobacterial infection is well known but the combination of pulmonary carcinoid and mycobacterial infection is rare. Case presentation We treated a 45-year-old female who presented with recurrent pneumonia. Chest X-ray showed a consolidation in the left upper lobe. The patient was treated with various courses of antibiotics without full recovery after six months. Computed tomography (CT) scan demonstrated a central mass in the left upper lobe. Bronchoscopy revealed an endobronchial, well-defined lesion that totally obstructed the left upper lobe bronchus. Bronchial biopsy showed typical carcinoid tumor. Rigid bronchoscopy with electrocautery was attempted, but we were unable to radically remove the tumor. Therefore lobectomy was performed. The surgical pathology specimen showed atypical bronchial carcinoid and consolidations in the lung parenchyma with granulomatous inflammation distally of the bronchial obstruction. Ziehl-Neelsen staining demonstrated acid fast bacilli indicative of mycobacterial infection. Conclusions This case history illustrates the importance of careful surgical pathologic examination, not only of the resected tumor, but also of the postobstructive lung parenchyma. Specific postobstructive infections such as tuberculosis or nontuberculous mycobacteria (NTM) can have clinical implications.

Background: A hernia is an aponeurotic defect that allows an organ to protrude from its normal cavity. Despite advancements in hernia care, hernia patients' experiences with care, as well as recurrence and complication rates, are frequently suboptimal. Adequate knowledge of the risk factors of a hernia could lead to a significant reduction in the prevalence of hernia. Therefore, the current study aimed to assess the awareness of the risk factors of abdominal hernias among adults in Saudi Arabia.Methodology: Our study is a cross-sectional analytic study to measure the level of knowledge, awareness, and practice of ventral and inguinal hernias in Saudi Arabia. The data was collected by using a valid pretested structured questionnaire taken from previous studies after getting writing approval.Results: In this study, we were able to collect data from 2611 individuals in different regions of Saudi Arabia, where 68.5% of the participants were females and 60.1% were aged between 18-29 years old. The prevalence of hernia among individuals in the current study was 9.2%, associated with participants older than 40 years old (19.1%), participants of the northern region (16.6%), illiterate individuals (30.0%), married (13.2%), and overweight or obese individuals (10.9% and 12.6%). In general, 53.7 % of the participants had a moderate level of knowledge, while 23.8% had a high level and 22.5% had a low level of knowledge. Conclusion:We found a moderate level of knowledge among adult individuals in Saudi Arabia about hernia. The prevalence of hernia was similar to those reported in previous studies; however, there is a higher incidence of risk factors in the current population.

Rationale Pleuroparenchymal fibroelastosis (PPFE) is a rare subtype of idiopathic interstitial pneumonias. PPFE mostly affects the upper lung zones and is characterized radiologically by pleural and subpleural fibrotic thickening with a reticular pattern. There is no established treatment for PPFE but lung transplantation can be considered for advanced stage. The gold standard for the diagnosis of PPFE is surgical lung biopsy (SLB) but the bronchoscopic transbronchial cryobiopsy (TBCB) is a less invasive alternative. Patient concerns We report here two cases in which the diagnosis of PPFE was established with the help of TBCB. Diagnosis and interventions Bronchoscopy with TBCB was performed under sedation with spontaneous ventilation and the help of an uncuffed ET tube. Outcomes Histopathology showed intra-alveolar fibroblastic proliferation with elastosis, which confirmed the diagnosis of PPFE. Lessons The current report demonstrates that TBCB can be a useful and safe tool to confirm the diagnosis of PPFE. According to our knowledge, this is one of few reports that shows successful diagnosis of PPFE by TBCB.

Cannabis is an annual herbaceous plant sometimes grown for decoration and used as bird food that looks like flax. The study wanted to determine if a Cannabis extract may have an effect on how anxious and depressed the female mice behaved. forty healthy female mice were divided into four groups. Tap water was administered to the first group (control). Ethanol was administered to second group (positive control). The third and four groups were given 1 and 2 mg/kg cannabis extract respectively. Treatment continued for 14 days. After therapy, the light–dark chamber, forced swimming, tail suspension, plus lamb and open field tests were done to assess anxiety and depressive behavior. The results indicated that the anxiety and depression were increased in treated females significantly compared to control. Biochemical results showed that DA,5-HT, AChE, GSH, GST, CAT and SOD were decreased while TBARS, corticosterone and cortisol were increased. In conclusion, cannabis effects this kind of females’ behavior but the mechanisms are not clear yet. We need more researches on this trend.