Nurses are qualified to provide effective nursing interventions in management of hypertensive patients and lower risk of cardiovascular disease; nurses-led interventions for hypertensive patients are measuring and monitoring blood pressure (BP); educate patients about importance of performing physical exercises, and select healthy diet as alkaline based diet. Eating more alkaline diet has many advantages as lowering blood pressure, lipid profile as cholesterol so improving cardiovascular health, moreover reducing body weight. The aim of the study: to examine the effect nurses-led interventions as intake alkaline-based diet on blood pressure, lipid profile and weight among patients with hypertension. Design: Quasi Experimental design. Setting: Medical outpatient clinic of Menoufia University Hospital, Egypt. Subject: Purposive samples of 100 hypertensive patients, they fulfill the inclusion criteria, 50 patients in each group (study and control). Tools: Three tools used to collect the current data; as follows: The tool (I): Interview questionnaire; Tool (II): Questionnaire for Alkaline -Based Diet. Tool (III): Physiological measurement. Results: the present results documented that; a highly significant difference was found between the two groups post intervention in relation to knowledge levels; blood pressure of the study group was lower than those of the control group after following the alkaline diet and water; also highly statistically significant differences were found between study and control groups at all measurements during post intervention in weight and all lipid profile variables except at the 3 rd measurement. Conclusion: consumption of alkaline diet and water had a good effect in reducing arterial blood pressure, body weight and blood lipids. Recommendation: replicate the study on large sample and establishing periodical alkaline diet programs with planned meals for hypertension, overweight and high blood lipids patients with continuous follow up.

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Submission of an original paper with copyright agreement and authorship responsibility.I (corresponding author) certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.Thanking you.