Highlights Coronavirus pandemic has created a global alarming situation. SARS-CoV shares sequence homology with bats, therefore, considered as origin. Scientists are burning midnight's oil to discover drug or vaccine against this deleterious virus. Medicinal plants should be explored to find a cure for this disease. Phyto-constituents are ubiquitously synthesised in plants, effective against SARS-CoV-2. Clinical trials for herbal formulations are promoted to find drug or vaccine. Other armours like physical fitness, balanced diet are promoted for boosting immunity.

Steroids are a pivotal class of hormones with a key role in growth modulation and signal transduction in multicellular organisms. Synthetic steroids are widely used to cure large array of viral, fungal, bacterial, and cancerous infections. Brassinosteroids (BRs) are a natural collection of phytosterols, which have structural similarity with animal steroids. BRs are dispersed universally throughout the plant kingdom. These plant steroids are well known to modulate a plethora of physiological responses in plants leading to improvement in quality as well as yield of food crops. Moreover, they have been found to play imperative role in stress-fortification against various stresses in plants. Over a decade, BRs have conquered worldwide interest due to their diverse biological activities in animal systems. Recent studies have indicated anticancerous, antiangiogenic, antiviral, antigenotoxic, antifungal, and antibacterial bioactivities of BRs in the animal test systems. BRs inhibit replication of viruses and induce cytotoxic effects on cancerous cell lines. Keeping in view the biological activities of BRs, this review is an attempt to update the information about prospects of BRs in biomedical and clinical application.

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