How to cite this article:Vivek Chail, Abhijit N, Rajan Balasubramanyam, Roohi Singh, Riyanka Chail. MR evaluation in non traumatic chronic wrist pain. International Journal of Contemporary Medicine Surgery and Radiology. 2020;5(1):A79-A84. study the epidemiology and most common causes of non-traumatic chronic wrist pain in the South Indian population and to study the spectrum of MRI features in those patients. Material and methods: Prospective descriptive study was done on 30 patients of both sex and age ranging from 11 to 70 years who presented with non-traumatic chronic wrist pain were selected for study and analyzed. Result: In our study, we found painful wrist is fairly equally common in almost age groups between 21 years to 60 years and is slightly more prevalent in the females compared to males We found infective and inflammatory causes formed the bulk of cases (~70%). Degenerative and inflammatory diseases were more common than infective disorders (36.7% as compared to 33.3%). Among inflammatory diseases, degenerative arthritis was the most common, followed by inflammatory tenosynovitis and rheumatoid arthritis. Bony lesions and soft tissue mass lesions formed the third-largest group (20%). The most common lesions included ganglion cysts and hemangiomas. We found fewer cases of avascular necrosis (6.7%) and carpal tunnel syndrome (3.7%). Conclusion: Early timely diagnosis by MRI not only helps in management but also help reduce long term disability. There has been a trend towards inflammatory/degenerative disorders due to the changing lifestyle and delayed presentation in developing countries.