Nanoparticles have aided in the development of nano-based sensors for diagnostic applications. However, use of nanoparticles in the development of sensing devices for multiple analyte detection is constrained due to their inability to detect several analytes with a single type of nanoparticle. The term “Janus particle” refers to micro or nanoscale particles that have been divided into sections or compartments, each of which has a distinct set of chemical or physical properties, producing multifunctional particles endowed with distinctive qualities. Furthermore, Janus particles have the ability to perform multiple functions within a single particle at the same time, with no interference from adjacent sections. This review focuses on the use of Janus particles in the fabrication of biosensors as well as in the investigation of various properties endowed by these Janus particles for their use as biosensors. It also discusses the various types of Janus particle-based biosensors that are currently available. Finally, the limitations of Janus particles in sensor technologies and their future scope have been discussed.
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Introduction: Water bore diseases like diarrhea, dysentery etc. are one of the major causes of death in many countries like India, Bangladesh, Indonesia etc. According to World Development Report (1992), 80% of the diseases in the world are related to water. According to a book published by World Health Organization and Organization for Economic Cooperation and Development, around 2.2 million of the 3.3 million water related deaths are caused due to diarrhea. The major reason for this problem is the unavailability of potable water to the masses. Absence of harmful chemicals, pathogenic microorganisms is some of the characteristic features of potable water. To reduce the risk of
This review focuses on nerve degeneration, owing to different nerve diseases or injuries being a major problem nowadays. The low regenerative capacity of the nerve leads to primary brain injury. Clinical therapies available were only able to stabilize lesion progression. Reversal of degeneration process and functional regeneration promotion were brought about by the implementation of nanotechnology to biology allowing cell tissue integration. Nanomaterials implemented in the delivery of drugs and bioactive materials treats specifically targeted cells. Nanomaterials made in contact with cells lead to stem cell therapy promoting stem cell differentiation and neurogenesis. Nanomaterials were also reviewed to be used as a potential scaffold material, being a neuroprotectant in nerve regeneration.
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