Background: Worldwide antimicrobial resistance is hugely increasing in the response of inappropriate antibiotic use. Our objectives were to assess knowledge of antibiotic use, misuse and antibiotic resistance in the slum community of Karachi. Methods: This Community-based cross-sectional study was carried out Shireen Jinnah Colony in Karachi for the period of six months from 1st January to 30th June 2017.Subjects of both genders were approached through convenient non-probability sampling technique. Subjects of both genders having age 15 years and above and who were willing to participate in the study were included. An adapted and validated questionnaire was used for data collection. Results: Out of total 120 subjects, the majority of 100 (83.3%) were males, 64 (53.3%) married, 36 (30%) were matriculate and 54.2% fell in the age group between 15-30 years of age. Majority of 77.5% participants never attended any seminar or workshop about antibiotic resistance. Most of 73.33% subjects answered that antibiotics are effective in treating both bacterial and viral infections. 60.83% of respondents purchase antibiotic with the prescription. 70 % of subjects knew about antibiotic adverse drug reaction. In addition, 60.83% stop the antibiotic medication when feeling better. Conclusion: The study concluded the lack of knowledge of the use of antibiotics and the unnecessary and improper use of the antibiotic may cause antibiotic resistance.

Background: Pneumonia is the leading cause of death of children under five years of age. The considerable number of children having pneumonia has difficulty to reach health services in the appropriate time due to their mother's failure to recognize the seriousness of their infection. Methods: Present cross-sectional study was performed by using a close-ended, adapted questionnaire comprising of 15 closed-ended items. Data was gathered through a convenient sampling method. The calculated sample size was 120 subjects of the female gender. Written consent was taken from each participant before filling of the questionnaire. Data was entered and analyzed in SPSS version 21.00. Results: Out of 120 subjects, 59.2% study participant was illiterate, 51.6% subjects were in the age group of 31 to 41 years. 15.8% of women had fair knowledge whereas 55.5% of women did not have knowledge about pneumonia. And 28.7% of women they did not know what is pneumonia. 60.8 % of respondents were unable to recognize sign and symptoms of pneumonia. Only 19.2% of participants know vaccination of pneumonia should be made essential for children. Conclusion: The study concluded that mother had scanty knowledge of pneumonia its preventive measure, and immunization. The government should also provide awareness through mass media, so that the mortality and morbidity rates can be reduced and many valuable lives can be protected.