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This paper presents a study on knowledge management and analysis of scientific Biotechnology trends in Venezuela, providing an overview of the science profile as well as regional development and its relation to issues of topics covered by Biotechnology based on the analysis of scientific publications for the period of 1995 to 2010. The survey was accomplished in database ISI/Web of Science using 60 terms selected by experts in Biotechnology and 803 register has been organized. Scientific indicators were produced using data/ text mining tools. It was possible to find a greater number of scientific publications in areas such as Ecology and Health, showing a greater frequency in these terms: DNA, PCR and Biodiversity. Results pointed out The United States of America as the main foreign partner-country of scientific publications followed by Spain and France. It was possible to verify cooperation network with others Latin American countries: Brazil, Colombia and Chile

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This article has the objective to describe and characterize the textile sector's technology transfer process, under the light of the core theoretical concepts, and the sector's dynamics and technological characterization. In addition to the technology transfer process, the article shows the main bottlenecks observed in the process, and possible actions for the involved actors to seek a better execution to the technologic transfer, thus reducing the acquired technology under-utilization, as well as the delay on its full use. Keywords:Textile industry, technologic innovation, transfer of technology. ResumoEste artigo objetiva descrever e caracterizar o processo de transferência de tecnologia do setor têxtil à luz dos conceitos teóri-cos básicos e da dinâmica e caracterização tecnológica do setor. Além da caracterização do processo de transferência tecnológ-ica, o artigo apresenta os principais gargalos observados no processo e possíveis ações para que os atores envolvidos busquem um maior efetivação da transferência tecnológica, diminuindo, assim, a sub-utilização da tecnologia adquirida ou a demora em sua plena utilização. Palavras-chave:Setor têxtil, inovação tecnológica, transferência de tecnologia.(1) Edi Braga Jr. -EQ/UFRJ, E-mail: edibraga@inpi.gov.br Endereço: Rua Mayrink Veiga no 9 -Centro Rio de Janeiro -RJ -Brasil

Many approaches are used to discover new antibiotic compounds, one of the most widespread being the chemical modification of known antibiotics. This type of discovery has been so important in the development of new antibiotics that most antibiotics used today belong to the same chemical classes as antibiotics discovered in the 1950s and 1960s. Even though the discovery of new classes of antibiotics is urgently needed, the chemical modification of antibiotics in known classes is still widely used to discover new antibiotics, resulting in a great number of compounds in the discovery and clinical pipeline that belong to existing classes. In this scenario, the present article presents an overview of the R&D pipeline of new antibiotics in known classes of antibiotics, from discovery to clinical trial, in order to map out the technological trends in this type of antibiotic R&D, aiming to identify the chemical classes attracting most interest, their spectrum of activity, and the new subclasses under development. The result of the study shows that the new antibiotics in the pipeline belong to the following chemical classes: quinolones, aminoglycosides, macrolides, oxazolidinones, tetracyclines, pleuromutilins, beta-lactams, lipoglycopeptides, polymyxins and cyclic lipopeptides.