TEMPO catalyzes the direct oxidation of aldehydes to mixed anhydrides in the presence of a carboxylic acid. The anhydrides can be converted in situ to esters, secondary, tertiary or Weinreb amides in high yield. Oxidation of the aldehyde directly to 2-propyl esters is also possible using only catalytic amounts of acid. The oxidation reactions are rapid and take place under mild conditions.

2,2,6,6-Tetramethylpiperidine-1-oxyl (TEMPO) catalyzes the direct oxidation of primary alkyl alcohols to symmetric esters at 1-2 mol% loadings. These rapid reactions take place at room temperature to afford the products in yields of 55-99%.

The preparation of a series of novel representatives of crown porphyrins, e.g. (I), is described.

The process is generally efficient under conditions A), where for the diols (V) formation of lactones is observed.

Synthesis and Properties of New α,β-Unsaturated Ketones Derived from Substituted 2-Quinolones. -Base-promoted condensation reaction of the 3-acetyl-2-quinolones, prepared from the 2-aminobenzophenones (I) and ethyl acetoacetate (II), with the aldehydes (IV) leads to the formation of the vinyl ketones ( V). -(VOSTROVA, L. N.; GERNEGA, S. A.; KIRICHENKO, A. M.; ONISHCHENKO, E. V.; ABRAMOVICH, A. E.; GRENADEROVA, M. V.; KLAD'KO, L. G.; Ukr.