IntroductionAdults with end-stage kidney disease (ESKD) treated with haemodialysis experience mortality of between 15% and 20% each year. Effective interventions that improve health outcomes for long-term dialysis patients remain unproven. Novel and testable determinants of health in dialysis are needed. Nutrition and dietary patterns are potential factors influencing health in other health settings that warrant exploration in multinational studies in men and women treated with dialysis. We report the protocol of the “DIETary intake, death and hospitalisation in adults with end-stage kidney disease treated with HaemoDialysis (DIET-HD) study,” a multinational prospective cohort study. DIET-HD will describe associations of nutrition and dietary patterns with major health outcomes for adults treated with dialysis in several countries.Methods and analysisDIET-HD will recruit approximately 10 000 adults who have ESKD treated by clinics administered by a single dialysis provider in Argentina, France, Germany, Hungary, Italy, Poland, Portugal, Romania, Spain, Sweden and Turkey. Recruitment will take place between March 2014 and June 2015. The study has currently recruited 8000 participants who have completed baseline data. Nutritional intake and dietary patterns will be measured using the Global Allergy and Asthma European Network (GA2LEN) food frequency questionnaire. The primary dietary exposures will be n-3 and n-6 polyunsaturated fatty acid consumption. The primary outcome will be cardiovascular mortality and secondary outcomes will be all-cause mortality, infection-related mortality and hospitalisation.Ethics and disseminationThe study is approved by the relevant Ethics Committees in participating countries. All participants will provide written informed consent and be free to withdraw their data at any time. The findings of the study will be disseminated through peer-reviewed journals, conference presentations and to participants via regular newsletters. We expect that the DIET-HD study will inform large pragmatic trials of nutrition or dietary interventions in the setting of advanced kidney disease.
Rationale & Objective: Clinical practice guidelines for dietary intake in hemodialysis focus on individual nutrients. Little is known about associations of dietary patterns with survival. We evaluated the associations of dietary patterns with cardiovascular and all-cause mortality among adults treated by hemodialysis.
Digitization of cultural heritage, has started to play a major role in sustainability; also, old maps investigations can be a valuable source of information. These should be carefully handled by archive workers and those who are studying them, because mycological content can increase both human health and environmental problems. These, together with the conditions in which are stored can deteriorate the composition of the cellulose fibers, respectively the canvas fibers on which are glued. Samples were collected from old maps dating to 1895 and 1910 by specific means and methods in order to investigate their mycological content which revealed the presence of Penicillium ssp and Fusarium spp. Scanning electron microscopy - analysis (SEM) was done for the mentioned materials in order to determinate the deterioration of the fibers.
In a society found in a continuous movement and development, children and teenagers face a more increased predisposition to adopt a messy lifestyle. Considering this background, the scope of the present study was to analyse the trends regarding the lifestyle of students from a school in Oradea Municipality, Bihor County, Romania. For the study were considered 591 students with ages comprised between 10 and 19 years. The research method used was that of the questionnaire which comprised 15 items regarding their perception of health, the practice of physical and sedentary activities, rest and nutritiouns habits. The interpretation of results brings forward the fact that students face great deficiencies regarding their health as a result of a messy lifestyle characterised by unhealthy nutritious habits, lack of physical activity and corresponding rest and the increase predisposition towards a sedentary lifestyle. The study materializes as an alarm signal regarding the unhealthy
Introduction: The Metabolic Syndrome is considered at present as one of the most important causes of mortality and morbidity at world level. Even if the uric acid is not part of any definition of the Metabolic Syndrome, the actual studies have shown strong associations between uric acid concentration and the Metabolic Syndrome or its components, the role of Uric Acid within the Metabolic Syndrome (MS) being increasingly investigated. Aims: We have analyzed recently published data that show the importance of hyperuricemia in MS, Cardiovascular Diseases, Chronic Kidney Disease. Conclusions: Uric Acid (UA) is a central player in MS progression and in cardiorenal pathology, which is why a multidisciplinary approach and a correct treatment are required, in order to obtain multiple benefits and, possibly, in the future, new therapeutic guidelines in approaching MS.
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