Malaysia has been considered an industrialized country and there is a demand for manpower in low-skilled jobs which usually filled by migrant workers. Therefore, this study focused to identify the level of alcohol consumption and its associated factors particularly among Nepali migrant workers in Shah Alam, Selangor. A cross-sectional study using a convenient sampling method was conducted among 233 Nepali migrant workers in Shah Alam, Selangor using a self-administered questionnaire. A validated scoring system by DASS 21 and The Alcohol Use Disorder Identification Test was employed. The results show that 60.09% of Nepali workers consumed alcohol with most of them are in low (31.43%) and medium (29.28%) risk level for alcohol consumption. The empirical findings reveal a significant association between income, education level, and peer pressure (p value<.001 respectively) with alcohol consumption. However, the study found no association between age, marital status, years of working, and body mass index (p value= 0.44, 0.19, 0.42, 0.40 respectively) with alcohol consumption. In a conclusion, most Nepali migrant workers consume alcohol but in low and medium risk severity for alcohol consumption. The results highlight sociodemographic factors such as income and education as well as peer pressure among important factors affecting alcohol consumption.

Hemophilia A is an X-linked recessive disorder which is due to factor VIII deficiency. It is a life-threatening coagulation disorder leading to complications including hemophilic-arthropathy, development of inhibitors, transfusion-related infections and profound psychosocial impact on the life of the patients. The aim of this study is to analyze the challenges in complications and the latest advancements in managing those complications. A thorough and systemic literature review was done to fulfill the objective of this study. The emergence of hemophilic arthropathy due to repeated symptoms of hemarthrosis is the most frequent complication found in haemophiliacs. Another critical complication, mainly seen in resource-poor settings is the development of lethal and severe bleeding episodes including episodes of intracranial hemorrhage. The development of inhibitors is another major challenge which often adds profoundly to the financial burden faced by hemophilia patients. Another major challenge is acquiring various transfusion-transmitted infections which was particularly more common few decades back. Studies also have revealed that there are myriads of significant psychosocial effects affecting the quality of life of hemophiliacs. Emerging treatments such as gene therapy, non-clotting factor concentrate products and extended half-life therapy can usher a new era in the management and the quality of life in hemophilia patients.