Carbon-Based Solid Acid Catalyzed One-Pot Mannich Reaction: A Facile Synthesis of β-Amino Carbonyl Compounds. -The three-component condensation of acetophenone (I), aromatic aldehydes (II), and aromatic amines (III) in the presence of catalytic amounts of carbon-based solid acid affords the title compounds (IV) in high yields. The green catalyst can be recycled after simple work-up and reused at least three times without substantial loss of activity. Besides the simple procedure, short reaction times and the easy work-up are further advantages. -(DAVOODNIA*, A.; TAVAKOLI-NISHABURI, A.; TAVAKOLI-HOSEINI, N.; Bull. Korean Chem. Soc. 32 (2011) 2, 635-638, http://dx.doi.org/10.5012/bkcs.2011.32.2.635 ; Dep. Chem., Fac. Sci., Islamic Azad. Univ., Zahedan, Iran; Eng.) -H. Hoennerscheid 28-077

A simple and efficient method for the synthesis of β-amino carbonyl compounds by one-pot three-component Mannich reaction of acetophenone, aromatic aldehydes and aromatic amines using a carbon-based solid acid (CBSA), as an effective and reusable catalyst, is described. The present methodology offers several advantages such as simple procedure with an easy work-up, shorter reaction times, and high yields.