Abstract:The critical success key of healthcare will lie in its ability to enhance the quality of patient care. Over the last view years, the computerized information system applied in the healthcare setting to increase the quality degree. Also, providing services for health individual and population to increase the probability of required outcomes. In this paper, we made an overview of healthcare information system (HCIS) from the total quality management (TQM) aspect. Therefore, the research includes the transformation challenges, the effect of HCIS on the healthcare quality, and what measurement used to assess the quality level of a healthcare environment. Consequently, the using of HCIS in the healthcare organization activities will lead to raising and improving efficiency, accomplish its goals and achieve an elevated level of quality.