Hipertensi merupakan faktor resiko utama untuk penyakit serebrovaskular seperti stroke, transient ischemic attack, penyakit arteri koroner (infark miokard, angina), gagal ginjal, dementia, dan atrial fibrilasi. Bila penderita hipertensi disertai dengan komplikasi dengan penyakit penyerta tertentu maka akan meningkatkan mortalitas dan morbiditas akibat gangguan kardiovaskularnya tersebut. Kegiatan pengabdian masyarakat ini bertujuan memberikan informasi dan edukasi kepada masyarakat tentang DAGUSIBU dengan harapan dapat mencegah atau menghambat terjadinya komplikasi kardiovaskuler. Pentingnya pemberian informasi dan edukasi tentang penggunaan obat yang benar mempengaruhi tingkat tercapainya tujuan pengobatan. Kegiatan ini diharapkan dapat meningkatkan kepatuhan pasien minum obat.  Partisipan pada kegiatan ini adalah seluruh lansia di Posyandu Kelurahan Bandungrejosari Kecamatan Sukun Kota Malang. Metode pendidikan masyarakat mengenai pentingnya kepatuhan minum obat antihipertensi ini diharapkan memberikan manfaat yang cukup efektif. Kartu DAGUSIBU obat ini akan digunakan sebagai media memantau tingkat kepatuhan minum obat antihipertensi. Peserta posyandu yang hadir kegiatan ini terdapat sebanyak  75% yang memiliki tekanan darah tinggi, hanya sekitar 38% yang minum obat antihipertensi. Para peserta posyandu meneriman kartu DAGUSIBU dan dimonitoring kepatuhan minum obat setelah satu bulan. Hal ini terlihat dari jumlah pasien posyandu yang patuh minum obat sebesar 60%. Hasil dari metode ini dapat dikatakan cukup efektif untuk memotivasi masyarakat  dalam menggunakan obat-obat antihipertensi secara tertib agar tidak jatuh pada komplikasi kardiovaskuler yang membahayakan.

Benign Prostatic Hyperplasia (BPH) is an enlarged prostate disease benign or a condition when the cells are present the prostate gland has an increased proliferation rate. There are several treatment options, including conservative (watchful waiting), medical, and surgery. Antibiotics in BPH cases can be prophylactic antibiotics or empiric antibiotics. This study was  an observational study. The samples were BPH patients who received antibiotics for period January - November 2019. The pattern of prophylactic antibiotic use shows that most of the patients received ceftriaxone therapy. Operation on BPH patients is TURP which is an operation classified into surgery with a clean-contaminated category so that prophylactic antibiotics are required. There are two patterns of use for empiric antibiotics in BPH patients: single (88%) and combination (12%). The pattern of single or combined use is given to patients depending on the complications of the disease and the patient's clinical condition. BPH cases occur in men mostly occurs at the age of 60-74 years. Prophylactic antibiotic therapy in BPH patients, namely ceftriaxone 1 gr IV once daily was 48 patients (90.6%), a broad spectrum. Meanwhile, the most use of empirical antibiotics with a single pattern is Ceftriaxone 1 gr IV twice daily (35.6%).

The search for new drugs to treat cases of infection continues. This is because the microorganisms that cause infection continue to mutate as a form of self-defense which causes resistance to antibiotics. One strategy for finding new drugs is through the exploration of active ingredients derived from plants that have been used empirically by the community. Impatiens balsamina is a plant that has been shown to have antibacterial, antifungal, antipruritic, and anti-allergic characteristics. The ethanol extract of the Impatiens balsamina flower contains secondary metabolites such as naphthoquinones, coumarin derivatives, flavonoids, steroids, quinones, and saponins. This study aimed to obtain the active ingredient of the Impatiens balsamina flower which is used as an herbal medicine in the treatment of infection. A multilevel extraction process was carried out using solvents of different polarity, so that fractions containing nonpolar compounds, semipolar compounds, and polar compounds were obtained. Then, each fraction was tested for antimicrobial potency. Antimicrobial testing in vitro was carried out using the disc diffusion method. The results showed that the secondary metabolites contained in the hexane fraction were terpenoids, flavonoids, polyphenols, and anthraquinone compounds. Secondary metabolites contained in the ethyl acetate fraction were alkaloids, terpenoids, flavonoids, polyphenols, and anthraquinone compounds. Secondary metabolites contained in the ethanol fraction were terpenoids, flavonoids, polyphenols, and anthraquinone compounds. The hexane fraction had the best percentage of inhibition and percentage of effectiveness against Staphylococcus aureus, Escherichia coli, and Candida albicans.